Studies and Analyses

Studies and Analyses

Enhancing Cardiovascular Research Through Ethnic Inclusion

Ethnic minority groups must be included in European health research

Despite the knowledge that ethnicity matters in cardiovascular disease, most studies of cardiovascular disease risk have not been designed to yield results that apply to different ethnic groups, report Meghna Ranganathan and Raj Bhopal (of Edinburgh University) in a new study in the international open-access medical journal PLoS Medicine.

To ensure that the results of research studies can be applied

Studies and Analyses

Cystic Fibrosis Study: Patients Show Less Lung Decline

Although cystic fibrosis patients in clinical trials had more severe illness, worse lung function, a lower weight level and more respiratory infection than non-participants, their involvement in research studies resulted in less lung function decline over a 7-year period.

The research results appeared in the first issue for January 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Christopher H. Goss, M.D.

Studies and Analyses

Walking Thrice Weekly Slows Peripheral Artery Disease Decline

A study in the Jan. 3 issue of the Annals of Internal Medicine shows that walking three times a week, even in an unsupervised exercise program, can significantly improve walking ability and slow progression of peripheral artery disease (PAD). PAD often causes leg pain because of impaired blood flow in the arteries.

The study of 417 men and women, conducted by researchers at Northwestern University Feinberg School of Medicine, indicates that those who walked for exercise three or

Studies and Analyses

Obesity Linked to Increased Kidney Failure Risk, UCSF Study Finds

Researchers at the University of California, San Francisco have determined that there is a strong relationship between being obese and developing end-stage renal disease, or kidney failure.

The long-range study found that the obese have up to a seven times greater risk of kidney failure than normal weight people, suggesting that obesity should be considered a risk factor for the condition, and that kidney failure is yet another consequence of obesity.

“There are more a

Studies and Analyses

Imaging study links key genetic risk for Alzheimer’s disease to myelin breakdown

A new UCLA imaging study shows that age-related breakdown of myelin, the fatty insulation coating the brain’s internal wiring, correlates strongly with the presence of a key genetic risk factor for Alzheimer disease.

The findings are detailed in the January edition of the peer-reviewed journal Archives of General Psychiatry and add to a growing body of evidence that myelin breakdown is a key contributor to the onset of Alzheimer disease later in life.

In addition

Studies and Analyses

Alcohol Ads Linked to Increased Drinking in Young People

Young people who view more alcohol advertisements tend to drink more alcohol, according to a new study in the January issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA Archives journals.

Young people are beginning to drink at an earlier age than ever before and their actions can have consequences ranging from poor grades to alcoholism and car accidents, according to background information in the article. Several studies have found an association between expos

Studies and Analyses

Brain Atrophy May Signal Dementia Risk in Healthy Seniors

Reduced volume, or atrophy, in parts of the brain known as the amygdala and hippocampus may predict which cognitively healthy elderly people will develop dementia over a six-year period, according to a study in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

New strategies may be able to prevent or delay the onset of Alzheimer’s disease (AD), the most common cause of dementia among older adults, according to background information in

Studies and Analyses

New Role for Prostaglandins in Zebrafish Embryonic Development

Prostaglandins – the fat-derived compounds linked to pain, inflammation, reproduction and cancer – can add another biological function to their extensive catalog.

A new study by Vanderbilt researchers reveals that prostaglandins help choreograph the intricate cell movements during early embryonic development in zebrafish, highlighting how perturbations in this pathway might influence human development and the spread of cancer. The results also may point to new molecular targets f

Studies and Analyses

One-Third of Depression Patients Find Remission in Study

Phase one of a four-phase, six-year study on treatments for depression – the largest of its kind and led by researchers at UT Southwestern Medical Center – showed nearly half fully recovered from their symptoms or had major improvement after treatment with an antidepressant medication.

Results of the study, involving nearly 3,000 patients at 41 sites, appear in the January issue of the American Journal of Psychiatry, include: A third of patients with major depress

Studies and Analyses

Study: Antidepressants May Lower Suicide Risk in Adults

Long-term, population-based study challenges FDA advisory

The risk of serious suicide attempts or death by suicide generally decreases in the weeks after patients start taking antidepressant medication, according to a new study led by Group Health Cooperative researchers and published in the January issue of The American Journal of Psychiatry. The study also found that the risk of suicidal behavior after starting 10 newer antidepressant medications is less than the risk posed by ol

Studies and Analyses

Night Eating Syndrome Common in Psychiatric Patients, Study Finds

Findings highlight need for screening and treatment

According to a study that appears in the January 1 issue of The American Journal of Psychiatry, researchers at the University of Pennsylvania School of Medicine and the University of Minnesota found that night eating syndrome is a common disorder among psychiatric outpatients and is associated with substance use and obesity.

Night eating syndrome is a condition that is characterized by two main features: excessive eat

Studies and Analyses

Re-Energizing Immunity: New Insights into Chronic Viral Infections

Findings provide potential strategy to improve therapeutic vaccines, T cell immunotherapy

Like boxers wearied by a 15-round bout, the immune system’s CD8 T cells eventually become “exhausted” in their battle against persistent viral infection, and less effective in fighting the disease.

In a study to be published Dec. 28 on the journal Nature’s website, researchers at Dana-Farber Cancer Institute and Emory University have traced the problem to a gene that turns off the

Studies and Analyses

Hyperbaric Oxygen Therapy Boosts Stem Cell Circulation

Recovery of injured and diseased tissue the ultimate goal

According to a study to be published in the American Journal of Physiology-Heart and Circulation Physiology, a typical course of hyperbaric oxygen treatments increases by eight-fold the number of stem cells circulating in a patient’s body. Stem cells, also called progenitor cells are crucial to injury repair. The study currently appears on-line and is scheduled for publication in the April 2006 edition of the American Jou

Studies and Analyses

Pouring Perception: How Glass Shape Affects Your Drink量

When pouring liquor, even professional bartenders unintentionally pour 20 to 30 percent more into short, squat glasses than into tall, thin ones, according to a new Cornell University study.

“Yet, people who pour into short, wide glasses consistently believe that they pour less than those who pour into tall, narrow glasses,” said Brian Wansink, the John S. Dyson Professor of Marketing, Applied Economics and of Nutritional Science at Cornell. “And education, practice, concentration a

Studies and Analyses

Vertebroplasty Reduces Back Pain and Boosts Activity Levels

A Mayo Clinic study has found patients report less back pain at rest and while active following vertebroplasty, a procedure in which medical cement is injected into painful compression fractures in the spinal vertebrae due to osteoporosis. Patients also reported improved function in their daily activities, such as walking, housework and getting dressed. The findings are published in the November/December issue of American Journal of Neuroradiology.

“These findings give us as good eviden

Studies and Analyses

Middle School Bullying Linked to High School Substance Abuse

Over the past decade, parents, educators and policy makers have become increasingly concerned about verbal and physical harassment in schools and the subsequent effects of peer victimization on teens. A recent study by Julie C. Rusby and colleagues from the Oregon Research Institute, published in the November 2005 issue of the Journal of Early Adolescence by SAGE Publications, found significant associations between peer harassment of students in middle school and a variety of problem behaviors, such

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