The early progression of chronic kidney disease in children and teens is poorly understood, but a national research team led by Johns Hopkins scientists is…
When selective cyclooxygenase 2 inhibitors (coxibs) were introduced a decade ago, they were widely hailed as a gastroprotective shield for NSAID users. Eventually, they were incorporated into the treatment guidelines of both the American College of Rheumatology and the Arthritis Foundation for patients at increased risk of GI complications.. Two gastroprotective strategies for patients prescribed NSAIDs were recommended–either coprescription of a non-selective NSAID with an acid-reducing medication or selection of a COX-2 inhibitor NSAID. Then, clinical studies began to uncover evidence that COX-2 inhibitors and other non-selective NSAIDs may increase the risk of heart attack and stroke. Spurred by these findings and other safety concerns, 2 of the 3 FDA-approved coxibs – rofecoxib, known to consumers as Vioxx, and valdecoxib, known to consumers as Bextra – were withdrawn from the market. Questions regarding the appropriate use of COX-2 inhibitors for arthritis patients – and broader questions regarding prescribing patterns of novel drugs soon after FDA approval – remain. …
It's long been thought that the body's own immune system, rather than reducing the symptoms, may make things worse. But now researchers at the Stanford…
A study of low-income housing residents has documented that the more television people say they watched, the less active they were, researchers from…
In a recent issue of the Proceedings of the National Academy of Sciences, Marcelo Magnasco, professor and head of the Mathematical Physics Laboratory at…
A unique nerve-stimulation treatment for epilepsy developed at UCLA offers a potential new alternative for tens of thousands of individuals unable to control…
A connection between fibromayalgia (FM) and cytokines (proteins that act as messengers between cells) was suspected after cancer patients treated with the…
A new Cornell study takes that view to task. “What we have shown is that the sound of a word can tell us something about how it is used,” said Morten…
Taking a family history is one of the most accessible genomic screens for breast cancer. However, a history of cancer on the paternal side may not be as well…
“Eszopiclone was well tolerated and significantly improved sleep onset, sleep efficiency, total sleep time and sleep quality over the study period,” said…
Professor Rhonda Griffiths, from the UWS School of Nursing, says the research arose from an inquiry by community health nurses who needed evidence to support a…
This study involved an investigation of 444 children of an MS-affected father or mother from 3,598 individuals in 206 families to compare the transmission of…
“Fuel cells are a genuine ‘clean’ technology,” says one of the study’s investigators, Professor Chris Hendry of the Cass Business School, London. “But…
The top reasons people give for not evacuating involve concerns about safety and security. More than two-thirds (68%) say their home is well-built and they…
A popular, computer-based card game is helping Oregon Health & Science University researchers monitor cognitive changes in the elderly, a new study shows. Scientists with the OHSU Oregon Center for Aging & Technology, or ORCATECH, found that a Solitaire-like game called FreeCell, when adapted with cognitive performance assessment algorithms, may be able to distinguish between persons with memory problems and cognitively healthy seniors….
For a paper to be published in the July edition of the journal Psychological Science, researchers gave participants material to remember in two experimental…
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