Under the right conditions, duckweed essentially farms itself. Wastewater, ponds, puddles, swamps—you name it. If there’s enough sunlight and carbon dioxide, the aquatic plant can grow freely. But that’s not all that makes it intriguing. Packed inside duckweed’s tiny fronds is enormous potential as a soil enricher, a fuel source, protein-rich foods, and more. New findings at Cold Spring Harbor Laboratory (CSHL) could help bring all that potential to life. CSHL Professor and HHMI Investigator Rob Martienssen and Computational Analyst Evan Ernst…

About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also overexpressed in many types of cancer. This makes it a promising target for cancer therapies. However, drugs that inhibit Plk1 have often proven ineffective. New findings by researchers led by Peter Lenart and Monica Gobran may help to improve therapeutic approaches. They discovered a previously unknown function…

Timely follow-up colonoscopies can reduce the mortality rate from colorectal cancer, and patient navigators can play an important role in facilitating screening, according to researchers at the U of A Cancer Center A University of Arizona Health Sciences-led study found that patients are more likely to get colonoscopies following abnormal stool test results if patient navigators assist them through the process. The paper, published in the Annals of Internal Medicine, showed that 55% of patients who were assigned to a…

In the fight against malaria, controlling the mosquito population is crucial. Several methods are currently used to reduce mosquito numbers and malaria risk. One of these includes the antiparasitic medication ivermectin. When mosquitoes ingest blood containing ivermectin, it shortens the insect’s lifespan and helps decrease the spread of malaria. However, ivermectin has its own issues. Not only is it environmentally toxic, but also, when it is overused to treat people and animals with worm and parasite infections, resistance to ivermectin…

People living with Long Covid often feel dismissed, disbelieved and unsupported by their healthcare providers, according to a new study from the University of Surrey. The study, which was published in the Journal of Health Psychology, looked at how patients with Long Covid experience their illness. The study found that many patients feel they have to prove their illness is physical to be taken seriously and, as a result, often reject psychological support, fearing it implies their symptoms are “all…

A study published in The American Journal of Pathology demonstrates that Piezo2 is a critical mechanoreceptor involved in stiffness-mediated profibrotic fibroblast phenotypes Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting the expression or function of Piezo2, a receptor that senses mechanical forces in tissues including stress, strain, and stiffness. The new study in The American Journal of Pathology, published by Elsevier, sheds light on the underlying mechanisms of…

Joseph Wilson, Anthony Hunsaker publish findings about Utah’s Pollinators in the journal ‘Diversity’ Wildlife conservation is critical to sustaining the planet’s biodiversity and health. But putting together a conservation plan is a tall order. First of all, you need to determine what species you’re conserving, along with their numbers, habitat needs, threats and how they fit into a complex ecosystem. As pollinators for native plants and food crops, bees play a pivotal role in our ecosystem, according to Utah State…

Research opens door to developing therapies for neurodegenerative diseases As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease, among others. Now, researchers at Washington University School of Medicine in St. Louis report they have found a way around that problem by targeting the network of vessels that drain waste from the brain. Rejuvenating those vessels, they have…

The research may enable the design of synthetic, light-activated cells for wound healing or drug delivery. Life takes shape with the motion of a single cell. In response to signals from certain proteins and enzymes, a cell can start to move and shake, leading to contractions that cause it to squeeze, pinch, and eventually divide. As daughter cells follow suit down the generational line, they grow, differentiate, and ultimately arrange themselves into a fully formed organism. Now MIT scientists have…

A new technique has enabled ultra-powerful magnetic resonance imaging (MRI) scanners to identify tiny differences in patients’ brains that cause treatment-resistant epilepsy. In the first study to use this approach, it has allowed doctors at Addenbrooke’s Hospital, Cambridge, to offer the patients surgery to cure their condition. Previously, 7T MRI scanners – so called because they operate using a 7 Tesla magnetic field, more than double the strength of previous 3T scanners – have suffered from signal blackspots in crucial…

The cells that make up the walls of the finest of all lymphatic vessels have a lobate, oak leaf-like shape that makes them particularly resilient to changes in fluid volume. A similar cell shape also supports mechanical stability in plants. This has been shown by researchers from Uppsala University in a new article published in the journal Nature. The lymphatic system consists of a network of lymph vessels that maintains the body’s fluid balance and supports the immune system. The…

Scientists at St. Jude Children’s Research Hospital found that removing one protein from tumors could help thwart cancer cells in multiple ways, enhancing immunotherapy effects Targeted inhibition of a “signal jammer” protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein voltage-dependent anion channel 2 (VDAC2) like a signal jammer to prevent the body’s anticancer systems from communicating with the immune system. The research also reveals the…

Newly described protein drives immune response, offers potential target for treatment Autoimmune diseases, which are estimated to affect more than 15 million people in the U.S., occur when the body responds to immune-system false alarms, and infection-fighting first responders are sent out to attack threats that aren’t there. Scientists have long understood how the false alarms get triggered, but the second step of dispatching the immune response has been a mystery. Now, scientists at Washington University School of Medicine in…

In experiments conducted at the University of São Paulo, tumor stem cells became less able to proliferate and invade tissues when the production of the prion protein was blocked by gene editing; the results suggest that the molecule could be a therapeuti Glioblastoma (GBM), one of the most aggressive types of brain cancer, is one of the greatest challenges for medicine, both because it is difficult to treat and because of its high mortality rate. In Brazil, although no exact…

Researchers led by CHLA’s Jonathan D. Santoro, MD, have identified signs of neuroinflammation and dysfunction of the blood-brain barrier among patients with Down syndrome Regression Disorder (DSRD). A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children’s Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in individuals with Down syndrome Regression Disorder (DSRD). The new study, “Evidence of blood–brain barrier dysfunction and CSF…

Data reveals that retention bans are a good first step, but won’t be enough to prevent continued decline Despite the fear they may inspire in humans, sharks have far more reason to fear us. Nearly one-third of sharks are threatened with extinction globally, mostly as a result of fishing. A team led by researchers at UC Santa Barbara discovered that mandates to release captured sharks won’t be enough to prevent the continued decline of these important ocean predators. These findings,…