MHH team successfully uses foreign immune cells against the human JC virus to cure seriously ill patients. Progressive multifocal leukoencephalopathy (PML) is a rare but serious brain infection. It gradually destroys brain tissue and often leads to death within a few weeks. It is caused by the human polyomavirus 2 – also known as the John Cunningham (JC) virus. In 2021, an interdisciplinary team at the Hannover Medical School (MHH) led by Professor Dr Thomas Skripuletz, senior physician at the…
MIT engineers look to manta rays… New research shows the filter-feeders strike a natural balance between permeability and selectivity that could inform design of water treatment systems. Filter feeders are everywhere in the animal world, from tiny crustaceans and certain types of coral and krill, to various molluscs, barnacles, and even massive basking sharks and baleen whales. Now, MIT engineers have found that one filter feeder has evolved to sift food in ways that could improve the design of industrial…
Not all plastics are equal — some types and colors are easier to recycle than others. For instance, black foam and black coffee lids, which are often made of polystyrene, usually end up in landfills because color additives lead to ineffective sorting. Now, researchers report in ACS Central Science the ability to leverage one additive in black plastics, with the help of sunlight or white LEDs, to convert black and colored polystyrene waste into reusable starting materials. “Simple, visible light…
Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are therefore separated from each other, even if they control the same gene, and switch it on in different parts of the body. A recent study from the University of Bonn and the LMU Munich challenges this idea. The findings are also important because gene…
…a more efficient, cleaner alternative to existing alternatives. Vehicles fueled by diesel lead to substantial carbon emissions that are challenging to decarbonize. In 2022, diesel fuel use made up about one-fourth of total U.S. transportation carbon dioxide emissions and about one-tenth of total energy-related carbon dioxide emissions, according to the U.S. Energy Information Administration. Joshua Yuan, the Lucy & Stanley Lopata Professor and chair of the Department of Energy, Environmental & Chemical Engineering in the McKelvey School of Engineering at…
Scientists at the European XFEL and DESY produce high-power attosecond X-ray pulses at megahertz repetition rates. Publication in Nature Photonics. A research team at European XFEL and DESY has achieved a major advance in X-ray science by generating unprecedented high-power attosecond hard X-ray pulses at megahertz repetition rates. This advancement opens new frontiers in the study of ultrafast electron dynamics and enables non-destructive measurements at the atomic level. Researchers have demonstrated single-spike hard X-ray pulses with pulse energies exceeding 100…
A new approach for diabetes therapies. Prof. Heiko Lickert is the director of the Institute of Diabetes and Regeneration Research at Helmholtz Munich, professor at the Technical University of Munich (TUM), and member of the German Center for Diabetes Research (DZD). Together with his team, they discovered Inceptor in 2021 and described its role as an inhibitor of the insulin signaling pathway. Both Inceptor and the insulin receptor are located on the surface of beta cells, where Inceptor can block…
Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes’ gaze. The study, published Nov. 22 in Nature Neuroscience, found that a simplified artificial circuit, based on the architecture of this neuronal system, can predict activity in the network. In addition to shedding light on how the brain handles short-term memory, the findings could lead to novel approaches for treating eye movement…
Researchers from the Institute for Neurosciences (IN), a joint center of the Miguel Hernández University of Elche (UMH) and the Spanish National Research Council (CSIC), who are also part of the Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED) and the Alicante Institute for Health and Biomedical Research (ISABIAL), have developed a cellular fractionation protocol. This method allows for precise analysis of the proteins located in synaptic membranes and in membranes outside the synapses, known as extrasynaptic membranes, in…
…uncover key mechanisms related to cognitive function. Discovery suggests broad implications for giving brain a boost. While it’s well known that sleep enhances cognitive performance, the underlying neural mechanisms, particularly those related to nonrapid eye movement (NREM) sleep, remain largely unexplored. A new study by a team of researchers at Rice University and Houston Methodist’s Center for Neural Systems Restoration and Weill Cornell Medical College, coordinated by Rice’s Valentin Dragoi, has nonetheless uncovered a key mechanism by which sleep enhances…
… mitigates three defects simultaneously for failure-free metal parts. University of Wisconsin–Madison engineers have found a way to simultaneously mitigate three types of defects in parts produced using a prominent additive manufacturing technique called laser powder bed fusion. Led by Lianyi Chen, an associate professor of mechanical engineering at UW–Madison, the team discovered the mechanisms and identified the processing conditions that can lead to this significant reduction in defects. The researchers detailed their findings in a paper published on November…
Curtin study. New Curtin University-led research has uncovered what may be the oldest direct evidence of ancient hot water activity on Mars, revealing the planet may have been habitable at some point in its past. The study analysed a 4.45 billion-year-old zircon grain from the famous Martian meteorite NWA7034, also known as Black Beauty, and found geochemical ‘fingerprints’ of water-rich fluids. Study co-author Dr Aaron Cavosie from Curtin’s School of Earth and Planetary Sciences said the discovery opened up new…
An inaugural measurement of the neutron will help physicists learn about nucleon structure and spin. Protons and neutrons–known collectively as nucleons–are the building blocks of matter, but one of these particles has received a bit more attention in certain types of nuclear physics experiments. Until now. New results published in Physical Review Letters describe a first-time glimpse of the internal structure of the neutron thanks to the development of a special, 10-years-in-the-making detector installed in Experimental Hall B at the…
Protein design aims to create customized antibodies for therapies, biosensors for diagnostics, or enzymes for chemical reactions. An international research team has now developed a method for designing large new proteins better than before and producing them with the desired properties in the laboratory. Their approach involves a new way of using the capabilities of the AI-based software Alphafold2, for which the Nobel Prize in Chemistry was awarded in 2024. Whether as building blocks, transport systems, enzymes, or antibodies, proteins…
New measuring node was placed off Boknis Eck today. One of the oldest marine time series stations in the world is located in Eckernförde Bay, just under two kilometres off the coast: Boknis Eck. Since 1957, data on the state of the Baltic Sea have been collected regularly from a ship and, since 2016, also from an underwater observatory on the seafloor. After the device disappeared in 2019, the GEOMAR Helmholtz Centre for Ocean Research Kiel today launched a new,…
Digital sensing-based monitoring system. Establishing a foundation for local technology commercialization in Vietnam. Korea Institute of Civil Engineering and Building Technology (KICT, President Kim Byung-Suk) developed a smart monitoring system that applies digital sensing technology to maintain and manage small- and medium-sized aging bridges. This study was conducted as an international matching joint research funded by KICT, and established a foundation for technology diffusion to ASEAN countries through joint research with University of Transport and Communications (UTC) in Vietnam. In general,…
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