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Health & Medicine

Environmental Enrichment Reverses Lead Poisoning Learning Deficits

Environmental enrichment that stimulates brain activity can reverse the long-term learning deficits caused by lead poisoning, according to a study conducted by researchers at the Johns Hopkins Bloomberg School of Public Health. It has long been known that lead poisoning in children affects their cognitive and behavioral development. Despite significant efforts to reduce lead contamination in homes, childhood lead poisoning remains a major public health problem with an estimated 34 million housing uni

Life & Chemistry

Crayfish Locomotion: Unveiling Neural Circuits in Swimming

Using computer models and experiments, researchers at the University of California, Davis, have identified the neurons and connections that are necessary for crayfish to swim.

“We can now pin down the essential components of the circuit,” said Brian Mulloney, a professor of neurobiology, physiology and behavior at UC Davis.

The nervous system controlling locomotion is highly tuned and very stable across different groups of animals, Mulloney said. That makes crayfish a good model

Health & Medicine

Stress and MS Flare-Ups: Insights from New Research

Avoiding stressful life events and learning effective coping skills may help avert flare-ups of multiple sclerosis (MS) in women with the disease, new findings suggest.

Researchers recruited 23 women with MS from the Multiple Sclerosis Clinic at the University of Pittsburgh Medical Center and followed them for a year. Each week, the women completed questionnaires asking about MS symptoms and life events, such as starting a new job, finding out that a child is doing poorly in school, having

Process Engineering

FaME38: Advancing Materials Research with X-Ray and Neutron Tech

Airplane wings or railway rails are examples of mechanical components constantly submitted to stress. They consist of materials (metal alloys) with properties that may change under stress. To understand and improve such materials, it is essential to observe them on a microscopic scale. The ESRF and the ILL make today a step forward into looking deep inside engineering components. Thanks to the use of complementary neutron and synchrotron X-ray beams, these two centres offer a unique tool to measure s

Life & Chemistry

Exosomes, novel antigen bearers in "antitumor vaccination", yield some of their secrets

Exosomes are minute, natural membrane vesicles secreted by various types of cells of the immune system. They are of enormous interest to oncologists, who are now using them in clinical trials as tumor-antigen bearers to trigger tumor rejection by the body.

On the basis of studies in vitro and in mice, INSERM doctors and research scientists at the Institut Curie proposed a novel mode of functioning of exosomes in the December 2002 issue of Nature Immunology. It seems that exosomes can indire

Life & Chemistry

Transgenic Nematode Resistance: Impact on Soil Organisms

A paper published today (26.11.02) in the December Issue of Journal of Applied Ecology by Cowgill et al describes the results of small-scale field trials that were used to assess the effect of PI-expressing potatoes on non-target soil organisms. The impact of a currently used PCN management option, the nematicide, aldicarb, on soil organisms was also studied.

The transgenic plants had an adverse effect on the fungal component of the soil microbial community, while the nematicide adversely

Information Technology

ESA’s Miniaturized Optics: A New Era for Planet Discovery

Internet traffic jams may become history if ESA succeeds in developing new technology to see nearby Earth-sized planets. Why? In looking for new ways to detect planets ESA is thinking that, instead of bulky mirrors and lenses in space, one can build miniaturised optical systems that fit onto a microchip. Such ‘integrated optics’ would also allow earthly computer networks to use high-speed routing of data streams as a natural spin-off.

Data moving around the Internet are like road traffic in

Life & Chemistry

New Study Uncovers Male Biological Clock Insights

Researchers at the University of Washington have discovered a cellular basis for what many have long suspected: Men, as well as women, have a reproductive clock that ticks down with age.

A recent study revealed that sperm in men older than 35 showed more DNA damage than that of men in the younger age group. In addition, the older men’s bodies appeared less efficient at eliminating the damaged cells, which could pass along problems to offspring.

“When you talk about having

Health & Medicine

Less Invasive IPI Technique Offers New Hope for Infertile Women

A woman with an obstructed cervix has been successfully treated for infertility using a technique known as intraperitoneal insemination (IPI). The technique, described in a case report just published in BMC Pregnancy and Childbirth, is less invasive and cheaper than alternative infertility treatments, which involve the harvesting of a woman’s eggs. Scott Sills from the Atlanta Medical Center and Gianpiero Palermo from the Cornell Institute for Reproductive Medicine describe how they wer

Health & Medicine

New Skin Cancer Detection Technique May Prevent Blindness

A new technique to aid early detection of skin cancer could also help fight serious eye diseases such as those caused by diabetes.

The technique has been developed at the University of Birmingham with funding from the Swindon-based Engineering and Physical Sciences Research Council. It involves using an innovative form of image analysis to tell the difference between skin cancer and other types of skin damage. This allows the cancer to be identified earlier and treated more quickly,

Studies and Analyses

Infants Learn Visual World Through Statistical Relationships

Baby’s first look at the world is likely a dizzying array of shapes and motion that are meaningless to a newborn, but researchers at the University of Rochester have now shown that babies use relationships between objects to build an understanding of the world. By noting how often objects appear together, infants can efficiently take in more knowledge than if they were to simply see the same shapes individually, says the paper published in the current issue of Proceedings of the National Academy

Agricultural & Forestry Science

From designer milk to ’green’ cows: predictions for milk and dairy products in the next 50 years

Old MacDonald will be surprised when he sees what’s headed for his dairy farm: specially bred cows that naturally produce low-fat milk, designer milk that boosts the immune system, and “green” cows — engineered to produce less methane to help stem global warming. All are among the changes predicted for the future of the milk and dairy industry over the next 50 years.

These and other developments are described in a special report commemorating the 50th anniversary of the Journal of Agr

Health & Medicine

Ovary Gene Discovery Sheds Light on Infertility Causes

Harvard Medical School researchers have uncovered an ovary gene whose absence from mouse egg cells produced severe pregnancy complications. The gene, Fmn2, which produces the protein formin-2, is similar in mice and humans and offers promise for understanding embryo loss, birth defects, and infertility in women. The study appears in the December Nature Cell Biology.

“As humans we are incredibly bad at producing eggs with the normal number of chromosomes, which is the leading cause of pregnan

Life & Chemistry

Mighty mice are less susceptible to muscular dystrophy gene’s effects

The Johns Hopkins scientists who first discovered that knocking out a particular muscle gene results in “mighty mice” now report that it also softens the effects of a genetic mutation that causes muscular dystrophy.

The findings, scheduled for the December issue of the Annals of Neurology and currently online, build support for the idea that blocking the activity of that gene, known as myostatin, may one day help treat humans with degenerative muscle diseases.

Working with mice ca

Information Technology

’Stippling’ speeds 3-D computer imaging

Ancient artists used a technique called stippling – in which pictures are created by painting or carving a series of tiny dots – to produce drawings on cave walls and utensils thousands of years ago.

Now engineers at Purdue University have created a new kind of computer-imaging software that uses stippling to quickly produce complex pictures of internal organs and other renderings. The method is 10 times faster than some conventional methods and could provide a tool for medical professionals

Health & Medicine

Link Between Generalized Anxiety Disorder and Peptic Ulcers

A new finding of a link between an anxiety disorder and peptic ulcer disease lends support to the view that this gastrointestinal disease and anxiety disorder may share a common link. In recent years, attention has focused on a more biological element with the identification of bacteria as a cause of peptic ulcers.

“The identification of Helicobacter pylori as an infectious cause of peptic ulcer disease has been considered by many to disprove the possibility that there is an important relat

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