If you sniff a rose this Valentine’s Day, your brain will recognize almost a hundred different molecules that collectively give the flower its heady scent-but how? Scientists are now discovering how the brain identifies odors and their mysterious counterparts, the pheromones. New research, to be presented today at the American Association for the Advancement of Science (AAAS) Annual Meeting and forthcoming in the journal, Science, explains how the mouse brain is exquisitely tuned to recognize an
Scientists at the Department of Global Ecology of the Carnegie Institution of Washington in Stanford, California, have found that climate trends significantly affect corn and soybean yields. David Lobell and Dr. Gregory Asner analyzed 17 years of data on crop yields, temperature, precipitation, and solar radiation throughout the U.S. for their study and published their results in the February 14, 2003, issue of Science.
The investigation showed that gradual increases in temperature cause si
When it comes to visual entertainment, three-dimensional viewing can be quite eye-opening. So, too, in science where a recent finding involving University of Iowa researchers used three-dimensional imaging to understand how a bacterial enzyme can take oxygen from air and use it to convert certain molecules into useful chemicals.
Specifically, the scientists saw that naphthalene dioxygenase, a bacterial enzyme, can bind oxygen (to iron) in a side-on fashion and add it on to naphthalene, a hy
Howard Hughes Medical Institute researchers are beginning to unravel how a mysterious sixth sense guides animal attraction. The scientists have made the first-ever recordings of patterns of brain activity in a mouse as it explores the sex and identity of a newly encountered animal.
The research team, led by Lawrence C. Katz, a Howard Hughes Medical Institute investigator at Duke University Medical Center, recorded the firing of neurons in the accessory olfactory bulb, part of a poorly under
In a demonstration of vaccine therapy’s potential for treating lung cancer, Dana-Farber Cancer Institute scientists and their associates report that a prototype vaccine boosted the natural immune response to tumors in a small group of patients with advanced non-small cell lung cancer (NSCLC). Moreover, the vaccine was found to be non-toxic and well-tolerated.
Published in the Feb. 15 issue of the Journal of Clinical Oncology, findings from the Phase I clinical trial will provide an impetus
Smithsonian scientist challenges results of recent study
Late last year, Frédéric Achard and colleagues published a controversial article in which they contended that earlier estimates of worldwide tropical deforestation and atmospheric carbon emissions were too high. In the February 14 issue of Science, Philip Fearnside from the National Institute for Amazonian Research in Brazil, and William Laurance from the Smithsonian Tropical Research Institute in Panama argue that the Achard st
The results from a longitudinal study of the relative frequency of various types of HIV mutations associated with the use of antiretroviral therapy (ART) were presented today at a meeting of leading AIDS researchers. The study showed that the prevalence of most key mutations associated with antiretroviral resistance have changed significantly from 1999-2002.
Specifically, the results showed that the prevalence of thymidine analog mutations (TAMs) and other key mutations associated with HIV
A research letter in this week’s issue of THE LANCET suggests that the pain-killer ibuprofen could diminish the well-known beneficial effects of aspirin on preventing cardiovascular disease. Aspirin makes platelets (blood-clotting cells) less ’sticky’ which is associated with fewer thromboses (clots). Aspirin therefore reduces the chance of heart attacks caused by coronary thrombosis and stroke (cerebral thrombosis). Previous laboratory research has suggested that ibuprofen in
Researchers from Imperial College London, University of Oxford, Kagoshima University (Japan) and University of the Ryukyus (Japan) have discovered the mechanism by which human T-lymphotropic virus type 1 (HTLV-1), the virus which causes adult T-cell leukaemia, spreads through the body.
Previously it was not understood how HTLV-1 was able to spread between cells and pass between individuals, but according to research published today in Science, the virus spreads by subverting normal T-cell (a
Scientists from the University of Leicester are taking revolutionary research further with the potential to offer new hope for knee-injury victims.
They are following up international research that aims to improve knee cartilage repair techniques, termed ‘chrondrocyte implantation’. The procedure, developed in Sweden ten years ago, involves growing a patient’s knee cartilage cells in a laboratory, which are then implanted through open knee surgery. Recent exciting developments revolve
Answer one of natural history’s most intractable questions
All of Madagascar’s living Carnivora (an order of mammals that includes dogs, cats, bears, hyenas and their relatives) descended from a single species that dispersed from Africa to Madagascar, apparently floating across the ocean barrier aboard wayward vegetation about 24 million to 18 million years ago. Previously, scientists believed that Madagascar’s seven living species of native Carnivora represented two to four
For the first time ever, a University of Alberta researcher has discovered that an animal species has changed its genetic make-up to cope with global warming. In the past, organisms have shown the flexibility–or plasticity–to adapt to their surroundings, but this is the first time it has been proven a species has responded genetically to cope with environmental forces.
Dr. Stan Boutin, from the Department of Biological Sciences at the University of Alberta in Edmonton, has been studying a
The number of circulating endothelial progenitor cells in an individual’s blood –– the precursor cells to those that line the insides of blood vessels –– may be an indicator of overall cardiovascular health, according to research by scientists at the National Heart, Lung, and Blood Institute (NHLBI) and Emory University School of Medicine. The research was published in the Feb. 13 issue of the New England Journal of Medicine.
The endothelial cells lining the blood vessels provide essen
Ames Laboratory researcher’s microscale channels steer neurons to rewire damaged nerves
Using microscale channels cut in an ultrathin biodegradable polymer, a researcher at the U.S. Department of Energy’s Ames Laboratory is working to regrow nerve cells. The technique, which may one day allow the paralyzed to walk and the blind to see, has been proven to work for peripheral nerve regeneration in laboratory rats.
Nerve cells are unlike most other biological tissue. When a
Study findings may offer prevention for avoiding those annoying spots caused by macular degeneration
The primary function of the retina is to capture light and initiate neural signals. The retina contains the photoreceptors, which are the site of sensory transduction in the visual pathway. Major landmarks in the retina are the fovea and macula, where light has a direct pathway to the receptors. An interruption of the blood supply to these landmarks can lead to age-related macular d
Green fluorescence allows isolating the beta cells for study of their behavior and number in the pancreas
Diabetes mellitus (DM) affects at least 16 million Americans, ranks seventh as a cause of death in the United States, and costs the national economy over $100 billion yearly. About 95 percent of persons with DM have type 2.
Type 2 DM is characterized by insulin resistance in peripheral tissues as well as a defect in insulin secretion by beta cells. Insulin regulates ca
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