Long-term use of new non-calcium, non-aluminum phosphate binder maintains bone health status
Shire Pharmaceuticals Group plc (NASDAQ: SHPGY, LSE: SHP.L, TSE: SHQ CN) announces that long-term treatment with FOSRENOL® (lanthanum carbonate), a new non-calcium, non-aluminum phosphate binder, does not promote bone softening or cause harmful effects on bone, according to data presented today at the American Society of Nephrology (ASN) annual meeting in St. Louis, Mo.
Even wit
Study shows weight-based REBETOL dosing in combination with PEG-INTRON significantly improves viral clearance in African-American patients with most-difficult-to-treat form of hepatitis C. WIN-R study provides important insights on improving hepatitis C treatment among African-Americans.
Twice as many African-American patients infected with the most difficult-to-treat form of chronic hepatitis C successfully cleared the virus when given a weight-based dose of REBETOL® (ribavirin,
Ever since the approval of Gleevec in 2001, a cancer-cell-specific drug used to treat chronic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called “targeted” medicines. The challenge of developing these medicines, which spare normal cells because they are designed to kill only cancer cells, has been complicated by the recognition that resistance to even targeted therapies can develop. In the case of Gleevec, for example, which disable
A world-leading team of Canadian scientists thinks that diet may play a critical role in limiting the body’s absorption of the toxic heavy metal mercury, and they’re lining up to test the idea on themselves.
The scientists from the NSERC-funded Collaborative Mercury Research Network (COMERN) have identified dramatic differences in the extent to which mercury from eating fish is absorbed by people in a variety of small Canadian communities.
Since 2000, COMER
Scientists have discovered that a cellular enzyme helps ferry HIV genetic instructions out of the cell nucleus where they can then be translated into proteins to begin their most destructive work. The cellular enzyme represents a potential new target for developing improved HIV drugs, say the researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and the McGill University AIDS Center.
Kuan-Teh Jeang, M.D., Ph
An errant enzyme linked to bipolar disorder, in the brain’s prefrontal cortex, impairs cognition under stress, an animal study shows. The disturbed thinking, impaired judgment, impulsivity, and distractibility seen in mania, a destructive phase of bipolar disorder, may be traceable to overactivity of protein kinase C (PKC), suggests the study, funded by the National Institutes of Health’s (NIH) National Institute of Mental Health (NIMH) and National Institute on Aging (NIA), and the
Children and adolescents with Obsessive Compulsive Disorder (OCD) respond best to a combination of both psychotherapy and an antidepressant, a major clinical trial has found. Supported by the National Institutes of Health’s (NIH) National Institute of Mental Health, the study recommends that treatment begin with cognitive behavior therapy (CBT), either alone or with a serotonin reuptake inhibitor (SSRI) antidepressant. The research spotlights the need for improved access to CBT, since m
New research shows that almost 3 percent of patients who went to hospital emergency rooms with chest pain – but who weren’t initially diagnosed with heart problems – went on to have heart attacks or other heart-related events within a month.
The study, by Wake Forest University Baptist Medical Center researchers and colleagues from seven other medical centers, will be reported in the December issue of Annals of Emergency Medicine and is currently available on-line. “Not all
Researchers at the University of Minnesota Stem Cell Institute are one step closer to understanding how blood cells develop through the use of human embryonic stem cells. The research better defines the conditions under which blood cell development occurs, making the process easier to replicate. The findings are published in the October issue of Experimental Hematology.
“These findings do more than give us a basic understanding of blood cell replacement–they allow us to consi
Overturning a scientific stereotype, researchers at the University of Illinois at Chicago have discovered a new role for a key protein involved in muscle contraction and shown it is present not just in the cytoplasm of cells but in the nucleus as well.
Actin has been pigeonholed as a molecular motor, explains Primal de Lanerolle, professor of physiology and biophysics at UIC. “Whenever cells move or divide, actin is involved, like its partner myosin.” “But in the nucleus,” de
It’s difficult to define
While children and adults have similar intellectual definitions of bullying, they may differ when applying them in reality, says a U of T researcher. “There are complexities that can interfere with how we view bullying incidents,” says Professor Faye Mishna of the Faculty of Social Work. “While we’re identifying important strategies and tips on how to deal with bullying problems, it’s important to also acknowledge how confusing it can be
Daily consumption drops
Employees in workplaces with no smoking restrictions smoke almost five more cigarettes daily than those whose workplaces completely ban smoking, says a study by the University of Toronto’s Ontario Tobacco Research Unit (OTRU). “Usually, the reason given for banning smoking in the workplace is to benefit non-smokers and this is a valid and important reason,” says OTRU’s Dr. Thomas Stephens. “What this study shows is that the bans also have health b
Study appears in the November issue of the Journal of American Dietetic Association
The popular DASH diet, established by the National Institutes of Health as a way to lower blood pressure and cholesterol levels, may have health benefits that go beyond its stated purpose of lowering people’s risk of heart disease, according to research published in the November issue of the Journal of the American Dietetic Association.
Researchers at Pennington Biomedical Research Center
SLU hepatologist to present findings at national conference in Boston
Interim study results indicate a certain drug combination treatment may suppress the hepatitis C virus more quickly than another. Researchers at Saint Louis University School of Medicine and six other research sites throughout the country found that combining the drug Pegasys® with ribavirin resulted in a greater reduction in hepatitis C viral levels than patients treated with Peg-Intron® and an equal dose of
To operate a nuclear power plant like Three Mile Island, hundreds of highly trained employees must work in concert to generate power from safe fission, all the while containing dangerous nuclear wastes.
On the other hand, it’s been known for 30 years that Mother Nature once did nuclear chain reactions by her lonesome. Now, Researchers at Washington University in St. Louis have analyzed the isotopic structure of noble gases produced in fission in a sample from the only known nat
Representatives of civic groups and local council members have been invited to a meeting on Monday 1st November to discuss how they see land and water uses in the Slea catchment changing in the future. The meeting is being organised by Sleaford Development Group at the Solo Club, Seaford and will brief those attending about a study investigating ways to manage nitrate pollution of groundwater.
The study, being carried out in collaboration with the School of Environmental Sciences a
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