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Physics & Astronomy

Tandem Ions: A Breakthrough in Next-Gen Atomic Clocks

NIST detects ’ticks’ in aluminum, with help from intermediary atom

Physicists at the Commerce Department’s National Institute of Standards and Technology (NIST) have used the natural oscillations of two different types of charged atoms, or ions, confined together in a single trap, to produce the “ticks” that may power a future atomic clock.

As reported in the July 29 issue of Science,* the unusual tandem technique involves use of a single beryllium ion to accurately se

Life & Chemistry

Unlocking Malaria: Key Protein Structure Revealed for Drug Design

Molecular ’handshake’ of key parasite protein seen as target for drug design and vaccine development

By determining the molecular structure of a protein that enables malaria parasites to invade red blood cells, researchers have uncovered valuable clues for rational antimalarial drug design and vaccine development. The findings are reported in the July 29 issue of the journal Cell.

Malaria causes approximately 400 million clinical cases and 2 million deaths annually

Studies and Analyses

Earliest Dinosaur Embryos Shed Light on Evolution and Parenting

Long-necked, herbivorous dinosaur’s embryo offers insights

The embryos of a long-necked, herbivorous dinosaur are the earliest ever recorded for any terrestrial vertebrate and point to how primitive dinosaurs evolved into the largest animals ever to walk on earth, say scientists from the University of Toronto at Mississauga (UTM), the Smithsonian Institution and the University of Witwatersrand, South Africa.

The discovery, published in the July 29 issue of Science, p

Studies and Analyses

Plague Bacteria Secrets: Pathway Exploited for Vaccine Innovation

Two studies by researchers at the University of Chicago show how the bacteria that cause the plague manage to outsmart the immune system and how, by slightly altering one of the microbe’s tools, the researchers produced what may be the first safe and effective vaccine.

Both papers — one published online July 28 in Science Express and one in the August issue of Infection and Immunity — focus on aspects of the type-III pathway, a molecular syringe that Yersinia pestis, the ba

Life & Chemistry

U of T Research Reveals Protein’s Role in Metabolism Control

Heme is key to protein’s work

University of Toronto researchers have gained new insight into how a specific protein may control circadian rhythms and metabolic processes, which has implications for treating cholesterol-related diseases.

U of T professor Henry Krause and his colleagues have identified heme, an iron compound, best known for its oxygen carrying capabilities in hemoglobin, as the molecule that allows the protein E75 to regulate a number of key developm

Life & Chemistry

Immune system’s distress signal tells bacteria when to strike back

The human opportunistic pathogen, Pseudomonas aeruginosa, has broken the immune system’s code, report researchers from the University of Chicago, enabling the bacteria to recognize when its host is most vulnerable and to launch an attack before the weakened host can muster its defenses.

In the 29 July 2005 issue of Science, the researchers show how this lethal organism detects interferon-gamma, a chemical messenger the immune system uses to coordinate its efforts to get rid

Physics & Astronomy

EGNOS Begins Initial Operations Phase with ESSP Leadership

The European Satellite Services Provider (ESSP) has begun the Initial Operations Phase of the European Geostationary Navigation Overlay Service (EGNOS), following the successful conclusion of negotiations with the European Space Agency.

During the Initial Operations Phase, the responsibility for providing the EGNOS signal and data will be transferred from the development agency (ESA) to the operator (ESSP). During this phase, the ESSP will technically qualify and optimise EGNOS op

Physics & Astronomy

Water Ice Discovered in Martian North Pole Crater

This image, taken by the High Resolution Stereo Camera (HRSC) on board ESA’s Mars Express spacecraft, show a patch of water ice sitting on the floor of an unnamed crater near the Martian north pole.

The HRSC obtained these images during orbit 1343 with a ground resolution of approximately 15 metres per pixel. The unnamed impact crater is located on Vastitas Borealis, a broad plain that covers much of Mars’s far northern latitudes, at approximately 70.5° North and 103° East.

Social Sciences

Research Reveals Importance of Caregiver Networks for Parents

Working parents rely on a network of caregivers – a source of positive bonds, stress when childcare is insufficient or inflexible

Despite the long-cherished belief that the nuclear family is independent and self-sustaining, most families with working parents depend on a network of care to manage work and family demands, according to research by Brandeis University sociologist Karen Hansen. More than half of all U.S. households with young children have two employed parents.

Life & Chemistry

Anti-inflammatory function of Alzheimer’s disease drugs revealed

Points way to development of more efficient treatment

The mechanism in anti-Alzheimer’s disease drugs that inhibits the production of a destructive, inflammation-causing protein in the brain has been revealed by researchers at the Hebrew university of Jerusalem.

Their work, described in a recent issue of the American journal, Annals of Neurology, is likely to lead to the development of more efficient drugs than are currently in use for treating Alzheimer’s D

Environmental Conservation

Global Map Reveals Decline in Big Fish Diversity

First global map reveals rapidly shrinking hotspots for tuna, marlin, swordfish

Diversity has declined by up to 50% over 50 years due to fishing

A new study released in Science (via Science Express http://www.sciencexpress.org) on July 28th reveals a striking downward trend in the diversity of fish in the open ocean – the largest and least known part of our planet. Teasing apart the effects of climate change and fishing over the past 50 years, the authors show a clear

Life & Chemistry

Chemical Industry Shines Brightly under Environment Agency’s Spotlight

The Chemical Industries Association (CIA) is encouraged to see that all of its member companies have scored well, if not better than last year, in the Environment Agency’s “Spotlight” report on Business’ Environmental Performance, published today.

Using the environmental protection (OPRA) methodology the Environment Agency assessed how well industry manages its regulated sites in terms of waste production, releases to air and discharges to water. In 2004, the chemical industry pro

Health & Medicine

Prostate Cancer: Men Prioritize Lifestyle in Treatment Choices

Maintaining lifestyle top of men’s list when choosing a prostate cancer therapy

Despite wanting to avoid undesirable side effects, nearly half of men with prostate cancer do not have enough information on the lifestyle impact of treatments

Nearly nine out of 10 healthy men say maintaining their lifestyle is the main priority if they had to receive a hormonal treatment for locally advanced prostate cancer, according to a new study.1 In reality, nearly half of men feel th

Power and Electrical Engineering

Italian Research Unveils New Method for Hydrogen Production

The next issue of Science will report a study that explains the mechanism for oxygen release by cerium oxide. This material is an important catalyst that favors many fundamental reactions that have profound implications for energy storage and environmental issues. These reactions include, for example, the purification of polluted gases and the production of hydrogen as new energy vector for fuel cells. The present study could inspire the design of new efficient catalysts for producing a large va

Technology Offerings

New Adjuvant Boosts Antiviral Vaccine Immune Response

A new adjuvant inducing an increased humoral and cellular immune response by enhancing antigen uptake and presentation.Further Information: PDF rubitec -…

Technology Offerings

Stem Cell Isolation: New Insights from Monoclonal Antibody 473HD

The monoclonal antibody 473HD reacts with a glycosaminoglycan epitop selectively expressed on radial gliacytes of which a subpopulation shows stem cell…

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