The study conducted in the laboratory of Don Cleveland, Ph.D., UCSD Professor of Medicine, Neurosciences and Cellular and Molecular Medicine and member of the…
When selective cyclooxygenase 2 inhibitors (coxibs) were introduced a decade ago, they were widely hailed as a gastroprotective shield for NSAID users. Eventually, they were incorporated into the treatment guidelines of both the American College of Rheumatology and the Arthritis Foundation for patients at increased risk of GI complications.. Two gastroprotective strategies for patients prescribed NSAIDs were recommended–either coprescription of a non-selective NSAID with an acid-reducing medication or selection of a COX-2 inhibitor NSAID. Then, clinical studies began to uncover evidence that COX-2 inhibitors and other non-selective NSAIDs may increase the risk of heart attack and stroke. Spurred by these findings and other safety concerns, 2 of the 3 FDA-approved coxibs – rofecoxib, known to consumers as Vioxx, and valdecoxib, known to consumers as Bextra – were withdrawn from the market. Questions regarding the appropriate use of COX-2 inhibitors for arthritis patients – and broader questions regarding prescribing patterns of novel drugs soon after FDA approval – remain. …
The findings, scheduled for publication as the cover story of the July 27 issue of the journal Nature, bring scientists one step closer toward realizing the…
The early progression of chronic kidney disease in children and teens is poorly understood, but a national research team led by Johns Hopkins scientists is…
The field campaign, called NASA African Monsoon Multidisciplinary Analyses 2006, runs from Aug. 15 to mid-September in the Cape Verde Islands, 350 miles off…
The Food and Drug Administration on Tuesday approved a new test studied at the University of Florida that could lead to better screening for the most common…
This line of scientific questioning points to ways in which neural systems compare to artificial ones, and can ultimately inform the design of artificial…
Developed at the University of Wisconsin-Madison, the faster technique will enable clinics to image more patients – particularly the burgeoning group of older…
A team of international researchers using NASA satellite images compiled an updated inventory of all “marine protected areas” containing coral reefs and…
HP Europe, Middle East & Africa (EMEA) and Junior Achievement-Young Enterprise (JA-YE) Europe will launch a new award to encourage young entrepreneurs to…
It is transmitted through the bite of the black fly, Simulium. Enviromental conditions such as humidity, rapid water rivers and altitude of Bioko favour the…
Following the Shuttle Discovery’s successful STS-121 mission earlier this month and Thomas Reiter’s arrival onboard the ISS, for the first time since May 2003…
They show the regions of Granicus Valles and Tinjar Valles, lying at approximately 26.8° North and 135.7° East. The northwest-aligned Granicus Valles and…
The paper, Notes on conformal invisibility devices, published in the New Journal of Physics (co-owned by the Institute of Physics and German Physical Society)…
But now, research just published in the advanced online issue of Nature Neuroscience 1, found that Rhesus macaques when listening to other monkeys’ calls…
Some large installations – sports centre, hotels and large industry – already use systems capable of generating both electricity and refrigeration for air…
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