… from Single Cells to Organoids. Researchers at the Fraunhofer Institute for Laser Technology ILT are working on new tools for the preparation and analysis of single cells and cell assemblies. The team developed the “Liftoscope”, a system for cell sorting for subsequent cultivation that can analyze and transfer biomaterials precisely and in a way that is gentle on cells. In addition to this system, further 3D bioprinting methods are increasingly finding their way into biotechnological research: Thanks to the…
In 2021, it had to be organized virtually, this year it will be held face-to-face in Bremen: In July 2022, the university will host the International Coral Reef Symposium (ICRS). There will be numerous accompanying public events starting in May. The ICRS will be opened by the Federal Minister for the Environment. “For us, the 15th World Coral Reef Conference is a very special event from several points of view,” says Professor Christian Wild from the University of Bremen, who…
Interdisciplinary top-level research in the field of tropical medicine is the goal of a new transnational network of excellence being established under the leadership of Professor Anna Förster of the University of Bremen. It is being funded by the German Academic Exchange Service (DAAD). For many years, the University of Bremen has been cooperating with one of the best universities in Thailand, Mahidol University in Bangkok. It is one of the strategic partners of the University of Bremen. A highlight…
… due to hyperpolarized nuclear magnetic resonance. Hyperpolarized nuclear magnetic resonance enables major medical advances in molecular diagnostics, for example for cardiovascular diseases or cancer therapy. Within the framework of the EU collaborative project “MetaboliQs”, seven partners coordinated by Fraunhofer IAF and NVision developed a microscopy method which, for the first time, enables the analysis of metabolic processes at the single cell level by means of diamond-based hyperpolarization. In addition, the consortium successfully demonstrated hyperpolarization using the PHIP method in…
Incorporating known physics into neural network algorithms allows them to discover new insights into material properties. Researchers at Duke University have demonstrated that incorporating known physics into machine learning algorithms can help the inscrutable black boxes attain new levels of transparency and insight into material properties. In one of the first projects of its kind, researchers constructed a modern machine learning algorithm to determine the properties of a class of engineered materials known as metamaterials and to predict how they…
Pitt chemical engineers show how tungsten oxide can be used as a catalyst in sustainable chemical conversions. Engineers rely on catalysts for a vast array of applications from food manufacturing to chemical production, so finding efficient, environmentally friendly catalysts is an important avenue of research. New research led by the University of Pittsburgh Swanson School of Engineering could lead to the creation of new, sustainable catalysts based on tungsten oxide and similar compounds. The project used computational simulations to understand…
A study shows how the National COVID Cohort Collaborative used XGBoost machine learning models to better define long COVID and identify potential long-COVID patients with a high degree of accuracy. Clinical scientists used machine learning (ML) models to explore de-identified electronic health record (EHR) data in the National COVID Cohort Collaborative (N3C), a National Institutes of Health-funded national clinical database, to help discern characteristics of people with long-COVID and factors that may help identify such patients using data from medical…
New approach paves the way for larger, more complex metalenses. Compact and lightweight metasurfaces — which use specifically designed and patterned nanostructures on a flat surface to focus, shape and control light — are a promising technology for wearable applications, especially virtual and augmented reality systems. Today, research teams painstakingly design the specific pattern of nanostructures on the surface to achieve the desired function of the lens, whether that be resolving nanoscale features, simultaneously producing several depth-perceiving images or focusing…
Just as it’s hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell’s environment. To solve that problem, researchers at Princeton Engineering have developed a method to elucidate a cell’s surroundings so that biologists can make more meaning of gene expression information. The researchers, led by Professor of Computer Science Ben Raphael, hope the new system will open the door to identifying rare cell…
Recently, a collaborated team led by Prof. LI Liang and Prof. LI Guanghai at the Institute of Solid State Physics (ISSP), Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Sciences (CAS), together with Prof. YAN Feng from Hong Kong Polytechnic University (PolyU) developed a new 2D-based photodetector, featuring on ultrafast photoresponse and broadband detection capabilities. The photodetector, which was introduced in a paper recently published in ACS Nano, was made from layered ternary telluride InSiTe3. Photodetectors with broadband detection capabilities…
A USC Stem Cell study in NPJ Regenerative Medicine presents intriguing evidence that large bone injuries might trigger a repair strategy in adults that recapitulates elements of skeletal formation in utero. Key to this repair strategy is a gene with a fittingly heroic name: Sonic hedgehog. In the study, first author Maxwell Serowoky, a PhD student in the USC Stem Cell laboratory of Francesca Mariani, and his colleagues took a close look at how mice are able to regrow large sections of missing rib—an…
Dynamic infrared tracer imaging uses affordable and widely available equipment to obtain the temporal resolution necessary to evaluate glymphatic flux within the brain. The glymphatic system facilitates fluid exchange in the central nervous system and clears dissolved wastes. This anatomically organized movement occurs primarily during sleep and is supported by astroglial neural cells via water channels called aquaporins. These channels line the perivascular pathways and facilitate cerebrospinal fluid and interstitial fluid exchange throughout the brain. Glymphatic dysfunction has been implicated…
An advanced MRI and PET study… Alzheimer’s disease (AD) is the most common type of dementia. An etiology of AD would be excessive accumulation of toxic forms of β-amyloid (Aβ), assumed to result from an imbalance between its production and clearance. Individuals with early-onset AD-related gene mutations show both increased production and decreased clearance of Aβ, whereas those with late-onset AD, which accounts for > 95% of cases, exhibit only decreased Aβ clearance. The ε4 allele of APOE gene is…
New material is capable of capturing trace amounts of benzene, a toxic pollutant, from the air and crucially use less energy than existing materials to do so. Researchers at University of Limerick, Ireland have developed a new material that has the ability to capture toxic chemicals from the air. The material is capable of capturing trace amounts of benzene, a toxic pollutant, from the air and crucially use less energy than existing materials to do so, according to the researchers….
PlasmidMaker has a user-friendly web interface with which researchers can intuitively visualize and assemble the perfect plasmid for their needs. Plasmids have extensive use in basic and applied biology. These small, circular DNA molecules are used by scientists to introduce new genes into a target organism. Well known for their applications in the production of therapeutic proteins like insulin, plasmids are broadly used in the large-scale production of many bioproducts. However, designing and constructing plasmids remains one of the most…
Based on similar technology to night-vision goggles, Australian researchers have developed a device that can generate electricity from thermal radiation. The sun’s enormous energy may soon be harnessed in the dark of night following a significant advance in thermal capture technology. Solar radiation heats the earth’s crust significantly during daylight hours, but that energy is lost into the coldness of space when the sun goes down. Now, researchers within the School of Photovoltaic and Renewable Energy Engineering at UNSW Sydney have successfully tested…
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