Lung cancer is the leading cause of cancer mortality worldwide and lung adenocarcinoma is the most common type. Many cases of lung adenocarcinoma are attributed to a mutation in a gene for the epidermal growth factor receptor (EGFR). Lung cancer with changes in EGFR is initially treatable with a family of chemotherapeutic agents called tyrosine kinase inhibitors (TKIs), such as gefitinib and erlotinib. However, patients often develop resistance to these drugs through the acquisition of additional changes or secondary mutations…
Stem cell derived neurons may allow scientists to determine whether breakdowns in the transport of proteins, lipids and other materials within cells trigger…
A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of…
Scientists at The Scripps Research Institute have determined the structure of a critical protein from the Ebola virus, which, though rare, is one of the…
Now, using mice as their model, researchers at Johns Hopkins have developed therapies that increase blood flow, improve movement and decrease tissue death and…
The 2009 H1N1 influenza virus used a new strategy to cross from birds into humans, a warning that it has more than one trick up its sleeve to jump the species…
NASA gave GPM the green light to proceed to the mission implementation phase in a review meeting chaired by NASA’s Associate Administrator Christopher Scolese.Building on the success of the Tropical Rainfall Measuring Mission (TRMM), a joint project between NASA and the Japan Aerospace Exploration Agency (JAXA), GPM will usher in a new generation of space-based observations of global precipitation, a key element of the Earth’s climate and also the primary source of freshwater. GPM is an international collaboration that currently includes NASA and JAXA, with anticipated contributions from additional international partners….
University of Rochester optics professor Chunlei Guo made headlines in the past couple of years when he changed the color of everyday metals by scouring their…
The silicon-based integrated system's features could help physicians quickly arrive at the right diagnosis for timely medical intervention in patients…
Almost a century after it was discovered in fruit flies with notches in their wings, the Notch signalling pathway may come to play an important role in the…
Jay Sa-Aadu and Ashish Tiwari, finance professors in the Tippie College of Business, and Jim Shilling, a finance professor at DePaul University, analyzed the…
New research led by biogeochemists Travis Horton of the University of Canterbury and Joel Blum of the University of Michigan lays the groundwork for assessing…
Published the week of Dec. 7 in the Proceedings of the National Academy of Sciences, the study, co-authored by Gayle Fritz, Ph.D., professor of anthropology in…
Junxia Shi, a graduate student in the laboratory of Lester Eastman, the John Given Foundation Professor of Engineering, developed the gallium nitride-based…
A split-personality chemical, estrogen is thought to protect neural circuits and boost learning and memory, while at the same time increasing cancer risk when…
Their study, published this week in the early online edition of the journal Proceedings of the National Academy of Sciences, was accomplished when the…
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