Rheumatoid arthritis (RA) is a chronic, systemic inflammatory
disorder that attacks the joints producing an inflammatory synovitis. About 1% of the world‘s…
Cacna2d2 gene variant leading to voltage-gated calcium channels with modified properties. entla-mice show ataxia, paroxysmal dyskinesia, and epileptic…
Human Norrin protein has been originally identified in the art as being a crucial
factor in the development of Norrie disease and is thought to be…
Epithelial cancers are among the most
frequent causes of death. Especially
pancreatic carcinomas are characterized
by early metastatic spread and…
Sulfolobus spp., a thermoacidophilic crenarchaeote, can be easily grown in
the laboratory and is interesting from a biotechnological point of view. Due
…
Carbohydrates are generated by photosynthesis in green plant cells. In higher plants
they are transported from green tissues (source tissue) to other parts…
Plants are an important source of pharmacologically active substances. The tropical
lianas of the families Dioncophyllaceae and Ancistrocladaceae are rich in…
Supply of novel, highly effective and non-toxic agents
– Improved prevention of biofilm-formation
– Treatment of infectious diseasesFurther Information: PDF Bayerische Patentallianz GmbH…
The molecular chaperone heat shock protein 90 (Hsp90) couples ATP hydrolysis
to conformational changes driving a reaction cycle that is required
…
Alzheimer‘s disease (AD), widely regarded
as the most common cause of dementia,
is a progressive neurological disorder. It
…
The invention is a lipid based delivery systems based on a vesicular phospholipid gel (VPG) formulation comprising tightly packed liposomes. Protein…
The invention is a lipid based implant, produced by screw extrusion. To achieve good extrudability, very homogeneous drug distribution, excellent mechanical…
Neuropathic pain is rather resistant
to conventional analgesics. Therefore,
different approaches must be
taken to treat neuropathic pain. One
…
A new category of borate compounds enables syntheses, which are difficult to realize, like the synthesis of duroplast precursors, ceramics and metal amides.
…
Thermostable, fast-folding esterase 2 from Alicyclobacillus acidocaldarius serves as a reporter enzyme to monitor in vivo or in vitro expression of eukaryotic…
Solubilization of hydrophobic drugs is a key issue in pharmaceutical industry. Currently, there are few non-toxic formulations available for drugs like…
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