World-renowned cardiologist to be honored for extraordinary contributions to interventional cardiology The TCT® 2025 Career Achievement Award will be presented to Stephan Windecker, MD, during Transcatheter Cardiovascular Therapeutics® (TCT®), the annual scientific symposium of the Cardiovascular Research Foundation® (CRF®). TCT® will take place October 25-28, 2025, in San Francisco, California at the Moscone Center. The award is given each year to an outstanding individual who has made extraordinary contributions to the field of interventional cardiology and has transformed cardiovascular care…
Findings identify opportunities for new treatments of Parkinson’s and related neurodegenerative disorders A longstanding mystery in Parkinson’s disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who also carry such variants do not. The prevailing theory has suggested additional genetic factors may play a role. To address this question, a new study from Northwestern Medicine used modern technology, called CRISPR interference, to systematically examine every…
Discovery in a magnetic crystal could enable breakthroughs in quantum tech A team of Rice University researchers reported the first direct observation of a surprising quantum phenomenon predicted over half a century ago, opening pathways for revolutionary applications in quantum computing, communication and sensing. Known as a superradiant phase transition (SRPT), the phenomenon occurs when two groups of quantum particles begin to fluctuate in a coordinated, collective way without any external trigger, forming a new state of matter. The discovery…
‘Optical rotatum’ describes new structure of light Beams of light that can be guided into corkscrew-like shapes called optical vortices are used today in a range of applications. Pushing the limits of structured light, Harvard applied physicists in the John A. Paulson School of Engineering and Applied Sciences (SEAS) report a new type of optical vortex beam that not only twists as it travels but also changes in different parts at different rates to create unique patterns. The way the light behaves…
New research explores geological processes along plate boundaries Being a geophysicist can sometimes feel like being a detective —uncovering clues, and then building a case based on the evidence. In a new article published in Science Advances, a collaborative team led by the Woods Hole Oceanographic Institution (WHOI), presents a never-before-seen image of an oceanic transform fault from electromagnetic (EM) data collected at the Gofar fault in the eastern Pacific Ocean. The National Science Foundation funded work reveals unexpected brine…
A research paper by scientists at Shanghai Jiao Tong University presented a novel channel-wise cumulative spike train image-driven model (cwCST-CNN) for hand gesture recognition. The research paper, published on Mar. 21, 2025 in the journal Cyborg and Bionic Systems, leverage a custom convolutional neural network (CNN) to extract both local and global features for classifying hand gestures, by decomposing high-density surface EMG (HD-sEMG) signals into channel-wise cumulative spike trains (cw-CSTs) and reconstructing these into two-dimensional images based on the spatial…
Light conditions in the morning before waking up affect restfulness Sleep is a necessary part of people’s daily routine, but modern lifestyles and technology have ushered in an era of decreased rest time and subsequent fatigue. Further, the bedroom environment, such as light, sound, and temperature, is important for a good night’s sleep, though this is often neglected in residential architecture. In search of a conclusive remedy, common sleep studies use artificial light that is easy to control. Osaka Metropolitan…
Hereon researchers develop innovative method to calculate predator-prey relationships more precisely Marine food webs are highly complex. Until now, researchers have been unable to understand exactly how they are affected by climate change, overfishing and other threats. Scientists at the Helmholtz-Zentrum Hereon in Geesthacht have now achieved a breakthrough. They have developed a new computer model that can be used to simulate food webs more accurately than ever before. The work, which has been published in the journal Nature Ecology…
With a prestigious Max Planck Fellowship (2025–2028), microbiologist Gabriele Berg from the Leibniz Institute for Agricultural Engineering and Bioeconomy (ATB) is launching a research collaboration with chemist Markus Antonietti at the Max Planck Institute of Colloids and Interfaces. Together, they’re developing a solution to soil exhaustion and infertility: a custom-made soil created in the lab from plant residues, enriched with carefully selected microorganisms. This biologically active soil is designed to restore microbial balance, support plant health, capture CO₂—and ultimately break…
Mechanical compression induces multicellular organization in archaeaIn a discovery that reframes our understanding of life’s fundamental organization, researchers at Brandeis University, the MRC Laboratory of Molecular Biology, and the Max Planck Institute for Biology Tübingen have found that mechanical compression can induce the formation of tissue-like multicellular structures in archaea. This novel finding, focusing on the haloarchaeon Haloferax volcanii, reveals a previously unknown pathway for the emergence of multicellularity within this domain of life, offering new insights into the evolutionary…
A recent paper published in Engineering titled “Machine Memory Intelligence: Inspired by Human Memory Mechanisms” explores a novel approach to AIby drawing inspiration from the human brain’s memory mechanisms. This research aims to address the limitations of current large models, such as ChatGPT, and paves the way for the development of more efficient and intelligent machines. Large models have achieved remarkable performance in various fields but suffer from several drawbacks. They consume excessive amounts of data and computing power, are prone to…
Cytochrome P450 (CYP) proteins are responsible for breaking down more than 80% of all Food and Drug Administration (FDA) approved drugs, reducing their effectiveness. However, how to prevent CYPs from doing this without off-target effects has puzzled researchers until now. Scientists at St. Jude Children’s Research Hospital have designed new drug frameworks that selectively target CYP3A4, one of the most critical CYP proteins. Structural insights from this work offer a roadmap for future drug developers to better evaluate drug interactions and selectively…
In a groundbreaking study published in Science, a research team led by Prof. YE Jian from the Institute of Microbiology of the Chinese Academy of Sciences has identified the first mechanism of citrus resistance to citrus greening disease, or huanglongbing (HLB). Utilizing artificial intelligence (AI), the team has also developed antimicrobial peptides that offer a promising therapeutic approach to combat the disease. This discovery addresses a long-standing challenge in the agricultural community—the absence of naturally occurring HLB-resistant genes in citrus….
Study in mice shows motivation can be restored with targeted treatments The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the unavoidable consequences of their declining physical health and extreme weight loss. But new research from Washington University School of Medicine in St. Louis challenges that long-held assumption, showing instead that these behavioral changes stem from specific inflammation-sensing neurons in the brain. In a study published April 11 in…
The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and proliferate during a viral infection. Their findings revealed novel mechanisms: the immune system amplifies its defense cells in a far more targeted way than previously believed. T-Cells Proliferate and Specialize During the Immune Response T-cells are crucial defense cells in the immune system. To effectively find and destroy infected cells in the body, rare…
Researchers have discovered antiferromagnetism in a real icosahedral quasicrystal, reinvigorating the search for antiferromagnetic quasicrystals Quasicrystals (QCs) are fascinating solid materials that exhibit an intriguing atomic arrangement. Unlike regular crystals, in which atomic arrangements have an ordered repeating pattern, QCs display long-range atomic order that is not periodic. Due to this ‘quasiperiodic’ nature, QCs have unconventional symmetries that are absent in conventional crystals. Since their Nobel Prize-winning discovery, condensed matter physics researchers have dedicated immense attention towards QCs, attempting to…
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