LJI researchers reveal a hidden side of how Ebola virus replicates inside host cells. New research in the journal Nature Communications gives scientists an important window into how Ebola virus replicates inside host cells. The study, led by scientists at La Jolla Institute for Immunology (LJI), reveals the inner workings of “viral factories,” clusters of viral proteins and genomes that form in host cells. The research team, which included experts from Scripps Research and UC San Diego School of Medicine,…
UC San Diego study shows hematopoietic stem cell transplants can protect against memory loss, neuroinflammation and β-amyloid build-up in Alzheimer’s mice. In the ongoing search for a cure for Alzheimer’s disease, a burgeoning branch of medicine is bringing new hope. Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system. In a new proof-of-concept study, scientists at University of California San Diego show stem cell transplants may also be a promising…
Scientists from the Keck School of Medicine of USC identify key cells involved in the process of cartilage regeneration in lizards— a discovery which could offer insights into novel approaches to treating osteoarthritis. A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails. This research, funded by the National Institutes of Health and published on August 10 in Nature…
While engaging in cell division research, Silke Hauf and members of her lab made a surprisingly quiet discovery. When cells express RNA, there is always some fluctuation, or noise, in how much RNA is produced. Hauf’s group found several genes whose noise dips below a previously established threshold, known as the noise floor, during expression. “We have solid data for this phenomenon,” said Hauf, associate professor in the Department of Biological Sciences at Virginia Tech. “There are some genes that are…
Researchers identify novel gelatinase substrates involved in astroglial barrier function: In neuroinflammation, immune cells such as leukocytes cross the blood-brain barrier. One key to this is the gelatinases matrix metalloproteinase (MMP)-2 and -9. Until now, the substrates of these enzymes involved in the process were unknown. Now, using a sensitive mass spectrometry-based secretome approach, researchers at the University of Münster and Bonn University Hospital (UKB) have succeeded in identifying hundreds of such molecules that are cleaved from the cell surface…
Research cruise with the METEOR starts. Expedition investigates hydrothermal systems in different water depths for the first time. Deep-sea hydrothermal vents, also often called black smokers because of their characteristic appearance, are a hotspot of life. The vents are often the only source of food, which is why symbioses between animals and microorganisms form here. Hydrothermal systems also exist in shallower waters. Food scarcity is not prevalent because of the availability of light and the associated possibility of photosynthesis, and…
Developing new materials requires significant time and labor, but some chemists are now hopeful that artificial intelligence (AI) could one day shoulder much of this burden. In a new study in the Journal of the American Chemical Society, a team prompted a popular AI model, ChatGPT, to perform one particularly time-consuming task: searching scientific literature. With that data, they built a second tool, a model to predict experimental results. Reports from previous studies offer a vast trove of information that…
What are the societal impacts of a company’s CO₂ emissions? What is the value of research and development for the community? To enable comparison and valuation of non-financial metrics, Impact Valuation factors translate sustainability figures into a uniform currency. However, organizations use different methods to evaluate their sustainability performance and most of these methods are not publicly available. With a strong commitment to comparability and transparency, WifOR has published its Impact Valuation factors. “Our mission is to set standards in measuring…
Graz University of Technology and University of Graz supply new forecasting service for the ESA’s Space Safety Programme. The effects of solar storms on the Earth’s atmosphere can cause satellites to crash. To prevent this from happening, the European Space Agency (ESA) is now using SODA, a forecasting service developed in Graz. After a successful test phase, the Satellite Orbit DecAy (SODA) service, which was jointly developed by TU Graz and the University of Graz, officially became part of the…
Dr. Jaeyeon Pyo’s team at KERI developed a method for printing structural colors through nanoscale 3D printing of diffraction gratings, selected as a cover article for ACS Nano. The world’s first 3D printing technology that can be used in transparent displays and AR devices has been developed, which implements the physical phenomenon of chameleon’s changing skin color or peacock’s beautiful feather color. Dr. Jaeyeon Pyo’s team at KERI has succeeded in realizing a three-dimensional diffraction grating that can precisely control…
Scientists to reveal the atomic-level workings inside the crushing and grinding of mechanical chemistry, with the potential to scale up their advances to make chemical manufacturing more sustainable and cost-effective. CUNY ASRC researcher Adam Braunschweig’s lab is part of a newly awarded $20 million center from the U.S. National Science Foundation to understand the atomic-scale mysteries of “crushing” chemistry. The multi-institutional award will establish the Center for the Mechanical Control of Chemistry (CMCC), which will conduct work to understand how…
Physical Review Letters published the new theoretical framework. Physicists have identified a mechanism for the formation of oscillating superconductivity known as pair-density waves. Physical Review Letters published the discovery, which provides new insight into an unconventional, high-temperature superconductive state seen in certain materials, including high-temperature superconductors. “We discovered that structures known as Van Hove singularities can produce modulating, oscillating states of superconductivity,” says Luiz Santos, assistant professor of physics at Emory University and senior author of the study. “Our work…
Based on the vanillin made usable for electricity storage in 2020, an AI-optimised prototype of an environmentally friendly electricity storage system is now being developed in an international project. In 2020, Stefan Spirk from the Institute of Bioproducts and Paper Technology at Graz University of Technology (TU Graz) described the research achievement with which he and his team had succeeded as a “ground-breaking success in the field of sustainable energy storage technologies” to make redox flow batteries more environmentally friendly…
Aspergillus fumigatus adapts to life in humans – and shapes their lung microbiome. Aspergillus fumigatus strains that infect humans have a significantly altered metabolism compared to other strains in the environment. At the same time, infection with the fungus leads to an apparent change in the human lung microbiome. Researchers at the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) came to this conclusion after using machine learning models to analyze genome data from about 250 fungal strains…
Came to stay: Once infected – always infected: Herpes viruses lie dormant in the body and can be reactivated by certain circumstances. The herpes virus HCMV is particularly widespread, yet despite its impact, well-tolerated and effective antiviral drugs or vaccinations do not exist. However, a team of researchers from FMP and Charité has now found out a lot about the interaction between HCMV and its host cells, which could also be useful for the development of antiviral agents. The paper…
In the 1980s, the Elbe estuary had largely lost its function as an estuarine filter due to heavy metal pollution. After decades, the estuary was able to recover from this, as a team led by doctoral student Louise Rewrie from the Helmholtz-Zentrum Hereon has discovered by measuring carbon and other parameters. Only in the last few years have biogeochemical processes in the Elbe River Estuary resumed naturally. The results recently appeared in the journal Limnology and Oceanography. River estuaries can…
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