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Current research findings on the processes that occur in the cell nucleus and during cell division in multicellular organisms are in the focus of a conference…
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This agreement is the basis for future events in China and Europe where the partners of both organizations can meet, establish contacts and exchange know-how…
University of Bremen developed a ceramic coating which comprises a special microstructure based on chemically inert oxide nanoparticles. Furthermore, the ceramic surface has a biofunctional effect due to a lysozyme which adheres to it. This results in a high grade of strength and resistance and has an extremely effective antimicrobial effect.
The new material provides effective surface protection from an environmental and health perspective against abrasion, corrosion and bacterial deposition. It is therefore suitable for use in processes involving the handling and processing of foodstuffs. It offers an alternative to the use of biocides and antibiotics in combating biofilms, and even prevents their formation altogether.
In addition to the antimicrobial effect, the surface provides all the advantages of a ceramic coating: strength, mechanical resilience and chemical inertia. By protecting the surface, this ultimately prolongs the service life of the systems, reduces the amount of cleaning required, and leads to cost-savings. Furthermore, the use of the body’s own lysozymes means that the surface is also suitable for coating implants for preventing contamination during operation.
Laboratory tests were carried out successfully to check the activity of the lysozymes immobilized on the ceramic surface. For that purpose, a continuous flow system was developed in which harsh ambient conditions were simulated using a supply of model microorganisms and aggressive ingredients. The micro-moulding method is universally applicable on a diverse range of surfaces and geometries. The surface must be adjusted and further developed for the relevant application.
Photodynamic tumour therapy (PDT) is a promising minimal-invasive method in the treatment of cancer. PDT is based on a method for the treatment of cancer with light in combination with a so-called photosensitizer.
In contrast to traditional photosensitisers, the chlorine compounds developed at and patented by the University of Bremen show amphiphilic (both hydrophilic and lipophilic) properties. The combination of lipophilic and non-ionic hydrophilic structure parts enables both good transport properties via the bloodstream and increased accumulation in the tumour tissue.
Due to the synthesis of the novel photosenitisers, exceedingly suitable candidates as active substances have been formed with the potential to improve the photodynamic therapy and its effectiveness. Moreover, the chemical process for the production of these compounds has been improved, enabling for the first time the clinical use of the structurally challenging photosensitisers in an economic way.
Initial experiments to verify the effectiveness have been carried out in vitro. The next step will be the verification in the animal model. We are looking for partner companies interested in the further development of the active substance using the patent.
TRMM is a satellite managed by both NASA and JAXA, the Japan Aerospace Exploration Agency. At NASA's Goddard Space Flight Center in Greenbelt, Md. Hal Pierce…
The achievement will allow researchers to conduct further studies to determine how the hormone helps plants respond to drought and other environmental stresses…
Researcher Dr Sarah Catalano has described 10 new parasite species− dicyemid mesozoans −, which live in the kidneys of cephalopods (cuttlefish, squid and…
The team, which includes several researchers from Texas A&M University, has had its work published in the current issue of Proceedings of the National Academy…
Temperature professionals from JULABO have several reasons to look back with satisfaction at their exhibition at Analytica (April 1 to 4, 2014 in Munich).
Led by Assistant Professor Takeo Ohsawa of NIMS and Associate Professor Taro Hitosugi of Tohoku University's AIMR, a research team has developed a new advanced…
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Technology that allows the direct conversion of sunlight, an ultimate renewable energy, into chemical energies (i.e., fuels) that can be condensed and…
A certain chloride channel, a membrane protein that allows the passage of the chloride ion, is of crucial importance in volume regulation. It is activated by…
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