Wieso verbindet man die Mobilfunkmasten untereinander nicht mit Kabeln? Grund dafür ist die Tatsache, dass Datenübertragung über weite Strecken bei…
Very special DNA lesions are DNA-protein crosslinks (DPCs) – proteins covalently linked to DNA. So far hardly anything was known about repair mechanisms…
Physicists of Johannes Gutenberg University Mainz (JGU) and the Graduate School of Excellence “Materials Science in Mainz” (MAINZ) have been able with the aid…
A very successful form of therapy by which antibodies inhibit tumor growth has not been available for animals so far. Scientists at the inter-university…
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the third most common cause of cancer related death worldwide. Cure of HCC is only possible by complete resection in early stages, but only 10–20% of tumors can be curatively resected and the risk of HCC recurrence is high. In addition, HCC is resistant to conventional radio- or chemotherapy. As a result, the prognosis of HCC remains poor and new therapies are urgently needed. The discovery of so far unknown immunodominant epitopes of the tumor-associated antigen Glypican-3 and the according HLA-A2 restricted T-cell-receptor enable the development of an adoptive T cell therapy for HCC patients. Adoptive T cell therapies showed very promising results in cancer therapy over the last years. The Science Magazine even awarded this technology as “Breakthrough of the year 2013”. Therefore, the current invention provides the tools for a promising new approach for the therapy of HCC.
“If you looked at metal under a microscope you’d see that it is composed of millions of closely-packed grains,” says Yuntian Zhu, a professor of materials…
Complex Regional Pain Syndrome (CRPS) is a serious condition affecting a limb after an – often small – accident or operation. It can cause severe pain lasting…
Figuring out how to survive on a lean-season diet of hard-to-reach ants, slugs and other bugs may have spurred the development of bigger brains and…
A German-Chinese research team has discovered a wasp with a unique nest-building strategy in the forests of southeast China:
The Vela pulsar provided a successful premiere for the new 28-metre Cherenkov telescope in Namibia. The pulsed radiation from Vela is the first to be measured…
Liquid water is an essential ingredient for life as we know it. Mars is one of the very few places in the solar system where scientists have seen promising…
The Siemens Industry Automation Division has extended the range of functions of the Simatic WinCC Scada (Supervisory Control and Data Acquisition) software in…
New research from Carnegie Mellon University is the first to show that brief mindfulness meditation practice – 25 minutes for three consecutive days –…
For certain applications, such as spectroscopic investigations on ions or atoms, however, (laser) light in the ultraviolet range is required. But this type of…
Scientists were able to implicate this new parasite, along with the ancient parasite Trichomonas gallinae, in the recent deaths of thousands of Pacific Coast…
Researchers at The University of Texas at Austin and the Technische Universitaet Muenchen created metamaterials with a million times stronger nonlinear optical…
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