Robotically assisted coronary artery bypass grafting (CABG) surgery is a rapidly evolving technology that shortens hospital stays and reduces the need for…
For the first time, researchers have found that exposure to radioactive iodine is associated with more aggressive forms of thyroid cancer, according to a…
When heart symptoms strike, men and women go through similar stages of pain but women are more likely to delay seeking care and can put their health at risk,…
A study published October 28 in the journal Biotropica represents a step toward a better understanding of the role antibiotic-bacteria play in the ecology of…
The 18th International ESAFORM Conference on Material Forming (ESAFORM 2015) is jointly organised by Graz University of Technology and VIRTUAL VEHICLE Research…
A new device facilitates the diagnosis for doctors: Through a visual analysis, they can reliably determine if they are dealing with carcinoma within a…
Chinese Hamster ovary (CHO) cells are commonly used as a mammalian expression system for the production of recombinant proteins. They are one of the few cell types that can be grown at high cell density as the cells are resistant to metabolic stress. However, given the considerable production costs it is of major importance to maximize the recombinant protein yield. The present invention allows for significantly increasing the recombinant protein expression level in CHO cells using a standard promoter. This is achieved by silencing the Galectin-1 gene through RNAi. The lentiviral Galectin-1-knockdown (>90%) increases the expression level of the protein of interest more than 1,5-fold. No further amendments are required.
Tropical Depression 9 made landfall in Mexico's Yucatan Peninsula late last week and lingered as a remnant low pressure area on Saturday and Sunday, Oct. 25…
How do our close relatives, the chimpanzees, acquire sufficient food when times are lean? By studying wild chimpanzees in the Taï National Park in Côte…
SLR Metaliks Ltd., an Indian pig-iron producer, has awarded Siemens Metals Technologies an order to supply a state-of-the-art bar rolling mill for its new…
“It took 50 years to show that this phenomenon indeed happens,” said Vesna Mitrovic, associate professor of physics at Brown University, who led the work. “We…
Re-examining longstanding beliefs about the physics of these devices, Princeton engineers have now shown that carefully restricting the delivery of power to…
Pulmonary hypertension is characterised by uncontrolled division of cells in the blood vessel walls. As a result, the vessel walls become increasingly thick….
Rosetta’s comet 67P/Churyumov-Gerasimenko is beginning to show a clearly visible increase in activity. While in the past months most of the dust emitted from…
Scientists have created cells with fluorescent dyes that change color in response to specific neurochemicals. By implanting these cells into living mammalian…
Scientists say they have identified in about 20 percent of colorectal and endometrial cancers a genetic mutation that had been overlooked in recent large,…