Open fractures occur when the broken bone protrudes through the skin, causing a puncture wound.
An interdisciplinary team of neuroscientists and neurosurgeons from the University of Rochester has used a new imaging technique to show how the human brain…
Columbia University Medical Center researchers have devised a way to replace the knee's protective lining, called the meniscus, using a personalized 3D-printed…
With global climate models projecting further drying over the Amazon in the future, the potential loss of vegetation and the associated loss of carbon storage…
“We looked at heavy metals in this study and found a strong association between exposure to low levels of cadmium and telomere shortening,” says Ami Zota, ScD,…
The present invention HerpHu-mAb provides a humanized anti-HSV antibody that is capable of neutralising HSV infections and inhibiting the cell-to-cell spread that is crucial during HSV reactivations.
HerpHu-mAb revealed as highly effective in prevention of ocular HSV infections as well as lethal infections under immune-suppressed conditions in the corresponding animal models. Moreover, HerpHu-mAb proved to be capable of overcoming drug resistant HSV infections. Since HerpHu-mAb specifically binds to a highly conserved surface antigen that is essential for the viral fitness, the development of drug resistance is most unlikely.
Due to the high infection rates of the population and due to the frequent reactivation of the lifelong persisting virus, HSV is of particular clinical relevance. A passive immunoprophylaxis is currently not available. A couple of experimental vaccines for active immunization against HSV1 and HSV2 showed no verifiable success.
HerpHu-mAb represents a new alternative for the treatment and prevention of HSV infections that is capable of overcoming drug resistances to conventional therapies.
Wei Chih was founded in 1982 and produces concrete reinforcing steel and structural steels for both the domestic market and for export to a number of countries…
The team has created the first modern germanium circuit – a complementary metal–oxide–semiconductor (CMOS) device – using germanium as the semiconductor…
As of Dec. 8, Super Typhoon Hagupit has caused up to 27 deaths. Early reports indicate the Philippines has been spared the widespread destruction caused by…
After testing a sample of abandoned oil and natural gas wells in northwestern Pennsylvania, the researchers found that many of the old wells leaked substantial…
Early narratives describe the decimation and dispersal of these fleets by the “Kamikaze” of CE 1274 and CE 1281 — a pair of intense typhoons divinely sent to…
Thanks to imagery from NASA’s Cassini spacecraft, we also know that Titan has rivers and lakes made of ethane and methane, as well as windswept sand dunes…
Using one of the most powerful lasers in the world, researchers have accelerated subatomic particles to the highest energies ever recorded from a compact…
Geologic storage of hydrogen gas could make it possible to produce and distribute large quantities of hydrogen fuel for the growing fuel cell electric vehicle…
Whether we’re paying attention to something we see can be discerned by monitoring the firings of specific groups of brain cells. Now, new work from Johns…
In the battle between native and invasive wetland plants, a new Duke University study finds climate change may tip the scales in favor of the invaders — but…
Feedback
