Over the past half century, the University Gothenburg has hosted one of the world's first prospective studies of aging. The subjects are 855 Gothenburg men…
Focal adhesions are cell junctions that act as mechanical linkages between the intracellular actin cytoskeleton of a live cell and the extracellular matrix (ECM). They have a wide functional scope. In this context Focal Adhesion Kinase (FAK) plays a pivotal role. FAK is often overexpressed in tumor cells and is partly responsible for the high tissue invasiveness of the infected cells. Now “small molecules” have been developed at the University of Konstanz, Germany, that interfere with the localization and thus with FAK functioning. Therefore, these molecules can be deployed in cancer treatment as well as in the prevention and treatment of restenosis via drug-eluting stents.
The novel FAK inhibitors are highly effective, cell-penetrating, easy to sterilize and can be produced through chemically defined synthesis.
An NIBIB grantee has developed an ultrafast camera that can acquire two-dimensional images at 100 billion frames per second, a speed capable of revealing light…
Inelastic neutron scattering experiments on a copper-oxide superconductor reveal nearly static, spatially modulated magnetism. Because static magnetism and…
In 2013 James Hone, Wang Fong-Jen Professor of Mechanical Engineering at Columbia Engineering, and colleagues at Columbia demonstrated that they could…
In these days, it was again tragically demonstrated that the Himalayas are one of the most active geodynamic regions of the world. Landslides belong to the…
Layered compounds are being investigated extensively due to their high theoretical specific capacities and relatively good cyclability. The electrochemical…
In new research published today by Nature Methods, scientists from the Hebrew University of Jerusalem and Harvard University have announced a “Neuronal…
The ultimate aim is to construct a multi-mission-capable space utility vehicle, while accelerating the overall development process for this critical capability…
The Malaysian shipping company Inai Kiara SDN BHD has unveiled the world’s biggest suction dredger. To allow use in water depths of up to 120 meters and ensure…
“You can imagine that with large protein complexes made from many different, smaller subunits there are many ways for them to be assembled. These can end up…
Scientists at NJIT's Big Bear Solar Observatory (BBSO) have captured the first high-resolution images of the flaring magnetic structures known as solar flux…
Astronomers from the University of Hawaii at Manoa, the University of California, Berkeley, the University of California Observatories, and Tennessee State…
A new study by Smithsonian scientists and colleagues published this week in the Proceedings of the National Academy of Sciences shows that species migrations…
Most of the time, we learn only gradually, incrementally building connections between actions or events and outcomes. But there are exceptions–every once in a…
A year before Albert Einstein came up with the special theory of relativity, or E=mc2, physicists predicted the existence of something else: cyclotron…
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