The Mars Atmosphere and Volatile Evolution (MAVEN) spacecraft was launched toward Mars on Nov. 18, 2013, to discover how the Red Planet lost much of its…
Solar flares are powerful bursts of radiation. Harmful radiation from a flare cannot pass through Earth's atmosphere to physically affect humans on the ground,…
A new method helps to make reliable and correct estimates in about 50% of patients, instead of only 10% of patients with the methods currently used. This…
Many tiny protein pores are found in the outer membrane of the pertussis pathogen, the bacterium Bordetella pertussis. Through these pores, the pathogen…
Islands are seen as natural laboratories for the study of evolution. They form isolated ecosystems with barriers to migration. Classical Island Theory predicts…
Down at the nanoscale, where objects span just billionths of a meter, the size and shape of a material can often have surprising and powerful electronic and…
Declining port handling volumes have been reported predominantly in some Asian ports as well as in the Baltic Sea.
Modern crocodilian mothers guard their eggs and young, but without any direct fossil evidence, scientists could only hypothesize that ancient crocodiles were…
The team of researchers led by Dr. Nataša Anastasov, head of the research group ‘Personalized Radiation Therapy’ at the Institute of Radiation Biology, created…
Researchers at Stanford University, the Max Planck Institute for Human Development, and the University of California, Davis, have investigated why it is so…
Treating people with type 2 diabetes, also known as “age-related diabetes” with antidiabetics reduces their risk for Alzheimer’s and other types of dementia….
Bad times for energy efficiency: German companies are planning to invest proportionately less in energy efficiency in the coming 12 months. The Energy…
VTT – Technical Research Centre of Finland acted as the partner and host for the 2015 event. VTT and its network PrintoCent constitute Europe’s biggest focal…
Spinal muscular atrophy (SMA) is an autosomal recessive disorder based on the loss of the survival motor neuron 1 (SMN1) genes. The severity of the disease is inversely correlated with the copy number of the main disease modifying gene SMN2.
In rare cases, siblings of SMA patients do not show SMA, although they carry exactly the same SMN1 and SMN2 gene status as their SMA affected relatives. So other genetic factors are able to fully protect homozygously SMN1-deleted individuals from developing SMA. The inventors found that this phenomenon might be caused by the overexpression of plastin 3, an actin-bundling protein, and/or low expression levels of the calcium sensing protein neurocalcin delta (NCALD). In vitro and in vivo studies show that inhibitors of neurocalcin delta (NCALD) are suitable for treating and preventing such disorders in a patient. Said inhibitors are, likewise, effective tools for in vitro neuronal differentiation and maturation, and restoration of impaired endocytosis.
X-rays from the Linac Coherent Light Source were used to measure the ultrafast response of DNA nucleobases to ultraviolet light. Researchers found that the UV…
Scientists for the first time tracked ultrafast structural changes, captured in quadrillionths-of-a-second steps, as ring-shaped gas molecules burst open and…
Feedback
