In recent years, two-micron lasers (0.002 millimetre) have been of growing interest among researchers. In the areas of surgery and molecule detection, for…
“We have found that this substance prevents the aggregation of tau proteins. This aggregation is typical of Alzheimer’s and other brain diseases classified as…
Supported by the Swiss National Science Foundation (SNSF), a team led by Frédéric Herman of the University of Lausanne has mapped the Franz Josef Glacier in…
Researchers at Sahlgrenska Academy, University of Gothenburg, demonstrated in January 2014 that antioxidants hastened and aggravated the progression of lung…
To minimize vehicle weight and fuel consumption while providing the highest level of crash safety, automotive bodies are reinforced with elements made from…
The present technology improves immunogenicity by treating DCs during maturation with the fungal-derived enzyme galactose oxidase. Hereby, a stronger physical interaction between DCs and T cells is achieved resulting in an at least 10-fold improved T cell priming capacity. In cell culture assays both human and mouse DCs showed enhanced T cell priming potential, the murine cells also in vivo.
Even the T cell stimulatory potential of mature DCs that were putatively activated up to a maximum was further improved by the galactose oxidase treatment. Hence, low affine T lymphocytes, as often found in the context of tumor antigens, can be activated and brought to proliferation too.
By improving T cell priming capability and therefore immunogenicity, this technology provides the opportunity to markedly enhance the classical DC maturation and accordingly to improve DC-vaccine approaches for example in tumor or HIV patients.
For the production of rechargeable batteries, it is desirable to use silicon as anode material in Li-ion batteries. The use of silicon anodes theoretically increases battery capacity tenfold compared to conventional graphite anodes. However, the attempt had previously failed, since the layers would expand by 300 to 400 % due to the storage of lithium ions in the Si bulk material. This induces a high residual strain and can destroy the bulk Si after only a few charge cycles. In addition, as a consequence of the irreversible reaction between the Si anode and electrolyte a layer of solid electrolyte interphase (SEI) can develop and lead to a low coulombic efficiency.
Scientists of the University of Stuttgart now succeeded in developing a porous semiconductor layer, which displays a pore distribution from 50 to 3000 nm and eliminates the residual strain. It can be manufactured in a continuous process.
The promise of big data lies in researchers' ability to mine massive datasets for insights that can save lives, improve services and inform our understanding…
The Atmospheric Infrared Sounder or AIRS instrument flies aboard NASA's Aqua satellite, which circles the Earth twice a day. AIRS gathers temperature data…
The workshop fosters the exchange of knowledge and experience between academics and industry in rapidly developing field of terahertz technology.
As many other stars, AU Microscopii is surrounded by a dust disk. Now researchers – including scientists from the Max Planck Institute for Astronomy in…
U Mic is located 32 light-years away in the southern constellation Microscopium. It is an optimal star to observe because its circumstellar disk is tilted…
In this study, published in the Journal of Geophysical Research, scientists compared ground-based videos of pulsating auroras–a certain type of aurora that…
As record ocean temperatures cause widespread coral bleaching across Hawaii, NOAA scientists confirm the same stressful conditions are expanding to the…
Today, magnetic resonance imaging allows more gentle, precise, and cost-effective heart disease diagnosis. However, the method has limitations when examining…
This process enables the production of functional fusion tissue of various sizes. One advantage over previous procedures is that it generates larger fusion tissue that is also improved in its differentiation and functionality. The invented fusion tissue is also suitable for screening for new substances, to test substances, to improve or validate known therapeutic substances, or to create new indications and applications for known substances.
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