Researchers at the Goethe University have discovered an important mechanism for superconductivity in a metallic compound containing ytterbium, rhodium and…
Diabetes, heart attacks, cartilage replacement, wound healing, brain tumours, Parkinson's disease: twelve research groups working on the National Research…
The invented substances have been characterized with regard to the inhibition of the cPLA2 (IC50 in the submicromolar range) and metabolic stability (tested in rat liver homogenates). The inventors are currently conducting such experiments with further, newly generated derivatives of the same inhibitor family. On behalf of the Westfalian Wilhelms-University of Muenster, PROvendis offers access to rights for commercial use as well as the opportunity for further co-development. The cPLA2 has been identified as target for the inhibition of inflammatory immune responses. The invented substances are of high interest for any pharma company with an immunological pipeline and may constitute the first-in-class cPLA2 inhibitors for systemic application.
Imagine a polymer with removable parts that can deliver something to the environment and then be chemically regenerated to function again. Or a polymer that…
Researchers at the University of Pennsylvania's School of Engineering and Applied Science and Perelman School of Medicine are looking for ways to refine this…
Modern optical technologies such as super-resolution nanoscopy enable to exactly image small structures and molecular processes, therefore, providing a…
Matthias Becker and Professor Albrecht Müller, two molecular biologists from the Julius-Maximilians-Universität Würzburg (JMU) in Germany, are interested in…
Scientists have been trying for years to make a practical lithium-ion battery anode out of silicon, which could store 10 times more energy per charge than…
The findings, scientists indicate, are some of the most compelling ever produced in the search for a therapy for ALS, a debilitating and fatal disease, and…
Acute lymphoblastic leukemia (ALL) is the most common cancer of childhood. In previous work done at CHLA, investigators reported that obese children diagnosed…
Although the propensity to take risks on average decreases over the lifespan, it is particularly susceptible to change in young adulthood up to the age of…
“Billions of tiny computers will in future communicate with each other via the Internet or locally. Yet power consumption currently remains a great obstacle”,…
Biological invasions by alien species are considered as being one of the main threats to biodiversity on earth. One of these invasions is taking place under…
This process allows difficult to reach dead volume areas deep inside components to be accurately ground and polished.
Though hundreds of enormous, high-velocity gas clouds whiz around the outskirts of our galaxy, this so-called “Smith Cloud” is unique because its trajectory is…
In today’s agriculture, hybrid plants are crucial for the sufficient production of food, feed, fuel and fiber. These crosses between two different varieties…
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