In 1965 Gordon Moore formulated the law that came to be named after him, which states that the complexity of integrated circuits doubles every one to two…
Scientists of the University of Duisburg-Essen developed a platform, which facilitates the detection of deletions and insertions as well as point mutations in target genes from a variety of sources against a huge background of wild type alleles, making a clear “Yes” or “No” output possible and thereby simplifying therapeutic decisions.
Neither expensive and complicated equipment nor specialized personnel is needed. The assay is robust and applicable in all laboratories equipped with an RT-PCR machine. It can easily be established for point of care (PoC) purposes.
This sensitive technology now enables clinicians to be independent of the scarce resource “tissue biopsy”. By using blood (ctDNA, cfDNA or CTC) it opens new non-invasive possibilities for monitoring the mutation status of patients before and during treatment as well as to detect disease relapse early. A European and a US patent have already been granted, other applications are pending.
During a joint research project scientists at the University of Stuttgart and the University of Konstanz developed an ECM with functional groups (clickECM) which is covalently and thus firmly bonded to surfaces via bioorthogonal ligation reactions. The fixed bonding obtained through the click reaction also ensures that the clickECM coating, e.g. when used for cell culture vessels, withstands extensive washing. The coating is highly stable and can be produced economically without any costly purification or isolation processes. The clickECM only differs from a natural ECM in terms of the introduced functional group.
How much are motorists prepared to pay for value-added services in an autonomous vehicle? This is the question posed by management consultants Horváth &…
A team of scientists from the Moscow Institute of Physics and Technology (MIPT), the National Research University of Electronic Technology (MIET), and the…
Climate scientists have long recognized the importance of forest conservation and forest regrowth in climate mitigation and carbon sequestration — capturing…
Earth could contain nearly 1 trillion species, with only one-thousandth of 1 percent now identified, according to the results of a new study.
Bathing a patient in LED light may someday offer a new way to locate tumors, according to Rice University researchers.
Notre Dame physicist Yong-Lei Wang and his colleagues have found a new way of designing artificial spin ices with controllable magnetic ordered states. The new…
A residential building, office block and experimental laboratory all rolled into one: NEST is a “living lab” in the truest sense of the word. Those who live in…
The researchers led by study director Annette Schürmann, Robert Schwenk and Anne Kammel of DIfE recently published their findings in the journal Human…
The group of Russian and French researchers, with the participation of scientists from the Lomonosov Moscow State University, has succeeded to synthesize…
While zinc sulfide nanoparticles – a type of quantum dot that is a semiconductor – have many potential applications, high cost and limited availability have…
In their study published online May 9 in the journal Oncogene, scientist Saraswati Sukumar, Ph.D.; her graduate student Wei Wen Teo; and their colleagues show…
Brandeis scientists Yasu Shima, Sacha Nelson and colleagues report in the journal eLife on a new approach for genetically identifying and manipulating these…
Quantum mechanics is the field of physics governing the behavior of things on atomic scales, where things work very differently from our everyday world.
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