…could help capture carbon directly from smokestacks. Electrochemical catalyst for converting CO2 to valuable products can stand up to an impurity that poisons current versions. A newly designed catalyst created by University of Toronto Engineering researchers efficiently converts captured carbon into valuable products — even in the presence of a contaminant that degrades the performance of current versions. The discovery is an important step toward more economically favourable techniques for carbon capture and storage that could be added on to existing…
Cancer is insidious. Throughout tumor progression, the disease hijacks otherwise healthy biological processes—like the body’s immune response—to grow and spread. When tumors elevate levels of an immune system molecule called Interleukin-6 (IL-6), it can cause severe brain dysfunction. In about 50%-80% of cancer patients, this leads to a lethal wasting disease called cachexia. “It’s a very severe syndrome,” says Cold Spring Harbor Laboratory (CSHL) Professor Bo Li. Left: Hyperactive neurons (pink) in the AP before treatment with antibodies (top) and CRISPR…
… a key gene in the progression and treatment of lung adenocarcinoma, has been discovered. The alteration of RNF144B especially affects the progression of lung adenocarcinoma tumours. According to the study, this gene’s low expression is related to a worse prognosis and greater resistance to conventional chemotherapy treatment. Research led by the Cancer Biology Laboratory of the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, in collaboration with the Center for Genomic Regulation and the Murcian Institute…
A new way to store carbon captured from the atmosphere developed by researchers from The University of Texas at Austin works much faster than current methods without the harmful chemical accelerants they require. In new research published in ACS Sustainable Chemistry & Engineering, the team developed a technique for ultrafast formation of carbon dioxide hydrates. These unique ice-like materials can bury carbon dioxide in the ocean, preventing it from being released into the atmosphere. “We’re staring at a huge challenge —…
Researchers at Tel Aviv University relied on principles of origami, the Japanese art of paperfolding, to develop an original and innovative solution for a problem that has been troubling researchers worldwide: positioning sensors inside 3D-bioprinted tissue models. Instead of bioprinting tissue over the sensors (found to be impracticable) they design and produce an origami-inspired structure that folds around the fabricated tissue, allowing the insertion of sensors into precisely pre-defined locations. The study was a joint effort of researchers from several…
What causes pulmonary hypertension. The blood pressure inside the lungs is typically much lower than in the rest of the body. Pulmonary hypertension occurs when the blood vessels within the lungs contract and the smooth muscle layer surrounding these vessels thickens. The disease puts constant stress on the right heart, as it needs considerably more strength to pump the blood through the lungs. As a result, the heart becomes enlarged and may eventually fail due to overload. “The causes of…
Interaction of monocytes and platelets decoded. Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have now discovered that platelets, also known as thrombocytes, communicate with monocytes and increase their inflammatory capacity. By understanding the platelet-monocyte interaction, they hope to improve the treatment of immune disorders and associated diseases. The results of the study have now…
… may facilitate infection, transmission in mammals. H5N1 virus did not efficiently transmit via respiratory route to ferrets. A series of experiments with highly pathogenic H5N1 avian influenza (HPAI H5N1) viruses circulating in infected U.S. dairy cattle found that viruses derived from lactating dairy cattle induced severe disease in mice and ferrets when administered via intranasal inoculation. The virus from the H5N1-infected cows bound to both avian (bird) and human-type cellular receptors, but, importantly, did not transmit efficiently among ferrets…
Researchers from Germany, Italy, and the UK have achieved a major advance in the development of materials suitable for on-chip energy harvesting. By composing an alloy made of silicon, germanium and tin, they were able to create a thermoelectric material, promising to transform the waste heat of computer processors back into electricity. With all elements coming from the 4th main group of the periodic table, these new semiconductor alloy can be easily integrated into the CMOS process of chip production….
A new theory has finally deciphered the physical mechanisms of fracture in soft materials. This revolutionary discovery will soon lead to new, defect-free materials that are more resistant and durable, thus “environmentally friendly”! The article Elastic Instability Behind Brittle Fracture was recently published by Physical Review Letters. “We have revealed that fracture propagates from the free surface of the material, starting from an elastic instability that breaks the symmetry of the object. Then, the rupture drastically extends with an intricate network of…
New compound supercharges naloxone… Every great superhero needs a sidekick. Now, scientists may have found a drug-busting partner for naloxone. Naloxone is an opioid antidote that has saved tens of thousands of lives by rapidly reversing opioid overdoses in more than 90% of cases in which it is used. But its powers are temporary, lasting only 30 to 90 minutes. The rise of potent, long-acting opioids such as fentanyl means that someone brought back from the brink can still overdose…
Scientists have made a significant breakthrough in creating a new method for transmitting quantum information using particles of light called qudits. These qudits promise a future quantum internet that is both secure and powerful. Traditionally, quantum information is encoded on qubits, which can exist in a state of 0, 1, or both at the same time (superposition). This quality makes them ideal for complex calculations but limits the amount of data they can carry in communication. Conversely, qudits can encode…
Physicists use magnetic fields to manipulate bacterial behaviour. Researchers at Finland’s Aalto University have found a way to use magnets to line up bacteria as they swim. The approach offers more than just a way to nudge bacteria into order – it also provides a useful tool for a wide range of research, such as work on complex materials, phase transitions and condensed matter physics. Bacterial cells generally aren’t magnetic, so the magnets don’t directly interact with the bacteria. Instead,…
Researchers at the University of Bonn have isolated a DNA molecule that is suitable for combating allergic contact dermatitis in mice. What is known as an aptamer binds to certain immune system messenger substances, rendering them ineffective. This even works if the active ingredient is applied to the skin in the form of an ointment. The working groups involved hope that aptamer creams such as this could also be suitable for treating other skin conditions. The results have now been…
How to improve transcription factors. Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to produce messenger RNAs from protein-coding genes. Denes Hnisz’s lab, in collaboration with Martin Vingron’s lab at the MPIMG, has discovered that human transcription factors don’t typically use their full potential to help transcribe mRNA. Instead, important protein regions within transcription factors encode chemical features that generate submaximal transcriptional activity. The findings, published in Nature Cell Biology, suggest simple…
Calyo, Benedex Robotics and Cranfield University have joined forces to improve safety in self-driving vehicles. The new partnership, part of the DRIVEN BY SOUND project led by Calyo, will develop a functional safety sensing platform based on 3D ultrasound, capable of operating effectively in even the most challenging environmental conditions. The new technology allows autonomous vehicles to detect their surroundings in 3D in real time. It complements existing sensing and safety detection systems, providing an additional layer of safety and…