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A quick glance at the trade fair industry is enough to see that 3D printing technology is the next big thing: new trade fairs such as RapidTech or formnext are…
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Experiments using the OMEGA laser at the University's Laboratory of Laser Energetics (LLE) have created the conditions capable of producing a fusion yield…
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Until now, unbreakable encrypted messages were transmitted via a system envisioned by American mathematician Claude Shannon, considered the “father of…
Solitons are localized waves that act like particles: as they travel across space, they hold their shape and form rather than dispersing as other waves do.
Research by Rice University Earth scientists suggests that virtually all of Earth's life-giving carbon could have come from a collision about 4.4 billion years…
The research is described today in the journal Nature Communications.
In ecology, monodominance is identified as a condition in which at least 60%, or often even 90% of trees in a natural forest belong to the same tree species….
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According to estimates by the American Skin Cancer Foundation, today more people develop skin cancer than breast, prostate, lung and colon cancer together….
An international group of researchers including Laura Bristow from the Max Planck Institute for Marine Microbiology in Bremen unveiled a surprising feature in…
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In his General Theory of Relativity, Albert Einstein predicted gravitational waves over a century ago; this year, they were detected directly for the first…
Among Gram-positive bacteria are some of the most dangerous pathogens for humans. Especially Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for a high percentage of hospital-acquired and deadly infections.
We have identified a naturally human-associated bacterial antibiotic producer strain (S. lugdunensis IVK28 wild type), which may act as a probiotic cure before patients enter hospital. Its application could avoid costly decolonization of human commensal bacteria before surgery.
From this bacterium we furthermore isolated a previously unknown class of peptide related structures with high potential as new antibiotics. Total chemical synthesis has been established.
The main compound Lugdunin shows very high potential against MRSA and other highly-resistant species like Enterococcus faecalis, E. faecium (VRE), Streptococcus pneumoniae and Listeria monocytogenes.
A patent application covering the chemical structures, the genetic background of the producer strain and the bioactivity of the new substances has been filed.
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