When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury. But in neurological disorders such as ALS and spinal muscular atrophy, or following spinal cord injuries, the mechanisms for moving life-essential RNA to injured sites within the cell fail. As a result, RNA molecules can’t get to where they are needed and damage becomes permanent. Researchers at Stanford have developed a technology for transporting RNA to specific locations within a neuron,…

Researchers at University of Colorado Anschutz Medical Campus lead study that identifies gene mutations and cell maturity as key factors in acute myeloid leukemia drug resistance An international study led by the University of Colorado Cancer Center has uncovered why a widely used treatment for acute myeloid leukemia (AML) doesn’t work for everyone. The findings could help doctors better match patients with the therapies most likely to work for them. The study was published today in Blood Cancer Discovery. Researchers…

Portable tech captures molecules in breath to aid medical care from diabetes to newborn development If you’ve ever sat waiting at the doctor’s office to give a blood sample, you might have wished there was a way to find the same information without needles. But for all the medical breakthroughs of the 20th century, the best way to detect molecules has remained through liquids, such as blood. New research from the University of Chicago, however, could someday put a pause…

Researchers at the Francis Crick Institute have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather than in the embryo, as previously thought. A better understanding of when these important cells develop could help researchers and clinicians understand and treat disorders that impact puberty and fertility. In the pituitary, a small gland located in the middle of the head and connected…