A team from The Hebrew University of Jerusalem has introduced a new method for megapixel-scale fluorescence microscopy through complex scattering media. This approach resolves high-resolution images from several tens of widefield fluorescence-microscope frames without requiring specialized equipment such as spatial-light modulators or intensive computational processing. By efficiently correcting distortions caused by light scattering, the technique allows for clear imaging of dense and challenging targets. Its compatibility with conventional microscopy setups, coupled with the use of established matrix-based techniques, makes it…

Piezoelectric coatings play a key role in the manufacturing of ultrasound microscopes that examine ever smaller semiconductor components and biological cell structures. However, the increasing demands on the quality and reproducibility of these coatings place high demands on the complex coating processes, which require many parameters to be precisely coordinated. In order to meet this challenge, Fraunhofer FEP is developing a digital twin of the coating process for piezoelectric thin films. This enables the digital mapping and optimization of the…

Together with Fiber Engineering GmbH, the DITF presents a process for the production of biodegradable plant pots. The products are cost effective and competitive. At the same time, the production process combats the spread of the invasive water hyacinth, whose biomass serves as the raw material for the plant pots. Combating an invasive species and reaping economic benefits at the same time? What sounds like a contradiction in terms has been successfully achieved by DITF scientists in a joint project…

Researchers at the University Medical Center Göttingen (UMG), Germany, have developed a new method that makes it possible for the first time to image the three-dimensional shape of proteins with a conventional microscope. Combined with artificial intelligence, One-step Nanoscale Expansion (ONE) microscopy enables the detection of structural changes in damaged or toxic proteins in human samples. Diseases such as Parkinson’s disease, which are based on protein misfolding, could thus be detected and treated at an early stage. ONE microscopy was…