Ifapsoriasin Fragments as Antimicrobial Peptides
The presence of ifapsoriasin (IFPS, fillagrin-2), a novel skin- and mucosaspecific S100 fusion type protein, at the surface of skin and mucosa, particularly where moisture-requiring soil bacteria may grow, reveals its potential as innate defense factor in the protection of body surfaces from infection with soil bacteria. This invention concerns peptide fragments of IFPS which are highly active against P. aeruginosa and other Pseudomonas species. IFPS may be used in the therapy of infectious diseases of epithelial organs and for infection prophylaxis at interfaces, especially of the skin, the nasopharynx, the eyes as well as the respiratory, gastrointestinal and urogenital tracts.
Further Information: PDF
Patent- und Verwertungsagentur für die Wissenschaftlichen Einrichtungen in Schleswig-Holstein GmbH (PVA SH)
Phone: +49 (0)431/8009937
Contact
Dr. Alexandra Baumgartner
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Sea slugs inspire highly stretchable biomedical sensor
USC Viterbi School of Engineering researcher Hangbo Zhao presents findings on highly stretchable and customizable microneedles for application in fields including neuroscience, tissue engineering, and wearable bioelectronics. The revolution in…
Twisting and binding matter waves with photons in a cavity
Precisely measuring the energy states of individual atoms has been a historical challenge for physicists due to atomic recoil. When an atom interacts with a photon, the atom “recoils” in…
Nanotubes, nanoparticles, and antibodies detect tiny amounts of fentanyl
New sensor is six orders of magnitude more sensitive than the next best thing. A research team at Pitt led by Alexander Star, a chemistry professor in the Kenneth P. Dietrich…