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New Enzyme Enables Selective Hydroxylation of Terpenes

A new enzyme of the family of cytochrome p450 was found which is able to stereo-selective hydoxylate terpenes at the 15beta-position. This enzyme can be applied in its purified form but preferably as a whole-cell catalyst. Compared to the state of the art, whether it is the total synthesis or chemical modification, this new method represents a consider-able saving of costs and alleviation. The procedure can be used for the conversion of di- and tri-terpenes and opens therefore access to a high number of new substances.

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Universität des Saarlandes Wissens- und Technologietransfer GmbH PatentVerwertungsAgentur der saarländischen Hochschulen
Phone: +49 (0)681/302-6340

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Dipl. Chem. Dagmar Vössing, Dipl.-Kfm. Axel Koch MBA, Dipl. Ing. Gerd Schneider

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