Prophylaxis and treatment of the skin disease <i>pityriasis</i>

Scientific research concerning the pathogenesis of pityriasis at the University of Giessen demonstrated that the disease-initiating event in pityriasis is the synthesis of pigments and fluorochromes which is dependent on one single enzyme. Inhibitors of this enzyme were identified which completely suppress pigment synthesis and are therefore presented here as a new approach for the prophylaxis and therapy of pityriasis (Pityriasis versicolor).<br>

The inhibitor does not primarily aim at antimycotic effects leading to an elimination of the fungus, but rather at an inhibition of the transamination process which is an important pathogenetic factor for disease development.

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