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Computational microscope peers into the working ribosome
The first study, in Proceedings of the National Academy of Sciences, concerns the intimate signaling between the ribosome and an elongation factor (EF-Tu) that is essential to the successful assembly ...
Studies and Analyses |
Read moreDiscovery of regulatory role of key molecule provides further step towards future gene therapy to control disease
The molecule, known as Lysyl-tRNA synthetase (or LysRS in brief) is one of the most ancient molecules in the cell, where it has long been recognized for its contribution in the translation of the info...
Life Sciences | Read moreScripps research scientists observe human neurodegenerative disorder in fruit flies
A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly...
Life Sciences | Read moreFruit fly steps in to fight human disease
"Now we have the opportunity to unravel the molecular mechanism behind Charcot-Marie-Tooth, as well as to start looking for substances with therapeutic value." The breakthrough is th...
Life Sciences | Read moreGenetic switch potential key to new class of antibiotics
Researchers have determined the structure of a key genetic mechanism at work in bacteria, including some that are deadly to humans, in an important step toward the design of a new class of antibiotics...
Life Sciences | Read moreThe World's First Discovery of genes in jigsaw-like pieces from an archaeon living in hot spring
A new insight into the origin of genesJapanese researchers have announced the world's first discovery of genes in jigsaw-like pieces from an archaeon living in hot spring, which gives new...
Life Sciences | Read moreWorm provides clues about preventing damage caused by low-oxygen during stroke, heart attack
They believe the finding could have implications for conditions such as stroke, heart attack and cancer. Sensitivity to low oxygen helps determine how damaging those medical conditions can be. The res...
Health and Medicine | Read moreA molecular identity crisis - a "Ribozyme without RNA"
This surprising discovery was made during a project supported by the Austrian Science Fund FWF that focussed on the enzyme RNase P. Contrary to accepted scientific theory, the project team from Vienna...
Life Sciences | Read moreScientists have discovered the cause of the hereditary disease PCH
Scientists from Cologne and Amsterdam have discovered the mutations in human genetics, which cause the hereditary disease ponto cerebellar hypoplasia (PCH) of the types 2 and 4.“In the case of...
Life Sciences | Read moreStudy Reveals Surprising Details Of The Evolution Of Protein Translation
In the study, researchers report that the dual functions of transfer RNA (reading the genetic blueprint for a protein, and adding a specific amino acid to the protein as it is formed) appear to have o...
Life Sciences | Read moreScientists Identify New Role for 'Power Plants' in Human Cells
The gene products, known as tRNAs, assemble amino acids for the production of proteins within mitochondria. If the mitochondrial tRNA genes are defective or missing, and proteins are not manufactured,...
Life Sciences | Read moreResearchers Observe Spontaneous 'Ratcheting' Of Single Ribosome Molecules
Their study, published in the journal Molecular Cell, reveals a key mechanism in the interplay of molecules that allows cells to build the proteins needed to sustain life.Cells use a variety o...
Life Sciences | Read moreArable land can have a negative impact on air quality
Fallow agricultural land and steppe-formation processes are evidently capable of having a much greater effect on global air quality than was previously assumed.This is the conclusion drawn by ...
Agricultural and Forestry Science | Read moreResearchers discover critical detail of cellular defense against genetic mistakes
The blueprint for the human body is encoded in genes. Gene expression is the process by which those blueprints are converted into proteins that make up the body’s structures and send its signals. When...
Life Sciences | Read moreResearchers See History Of Life In The Structure Of Transfer RNA
The study, co-written by Gustavo Caetano-Anollés, a professor of crop sciences, and postdoctoral researcher Feng-Jie Sun, appears March 7 in PLoS Computational Biology. Caetano-Anollés is an affiliate...
Life Sciences | Read more
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