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301 matches found for "fibrosis"

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Causative gene of a rare disorder discovered by sequencing only protein-coding regions of genome

For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder. Mendelian disorders, ...

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The use of stem cells in regenerative medicine may also be detrimental for health

Researchers aimed to investigate whether the mononuclear cell fraction of human cord blood (HUCBM cells), which contains stem cells, might be useful in hepatic regenerative medicine. Both histological...

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Study Shows How Carbon Nanotubes Can Affect Lining of the Lungs

Now a collaborative study from North Carolina State University, The Hamner Institutes for Health Sciences, and the National Institute of Environmental Health Sciences shows that inhaling these nanotub...

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Suppressing a gene in mice prevents heart from aging, preserves its function

Scientists prevented age-related changes in the hearts of mice and preserved heart function by suppressing a form of the PI3K gene, in a study reported in Circulation: Journal of the American Heart As...

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Northeastern Biologist Receives $5.5 Million NIH Grant to Study Tolerant Bacteria

The five-year project, part of the NIH Director’s Transformative Program (T-R01), will focus on three types of disease-producing bacteria to determine how dormant subpopulations of these microorganism...

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Scientists identify gene for short-circuiting excess mucus in lung disease, common colds

The discovery was reported in a study posted online Sept. 14 by the Journal of Clinical Investigation. The new research sheds light on what has been a medical mystery - the precise biological reasons ...

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Gene variant heightens risk of severe liver disease in cystic fibrosis

Those who carry a particular variant of the SERPINA1 gene (also known as alpha-1-antitrypsin or alpha-1-antiprotease) are five times more likely to develop cirrhosis and other liver complications than...

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U-M researchers discover therapeutic target that could help patients with pulmonary fibrosis

A diagnosis of Idiopathic Pulmonary Fibrosis is not much better than a death sentence: there is no treatment and the survival rate is less than three years.But researchers at the University o...

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Researchers Find Target for Pulmonary Fibrosis

But researchers at the University of Michigan have discovered that targeting of a novel gene utilizing genetic and pharmacologic strategies was successful in treating pulmonary fibrosis in mice and wi...

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Mutations in gene linked to ciliopathies

Ciliopathies are a newly emerging group of diseases caused by defects in the function or structure of cellular primary cilia, which are small, cellular appendages of previously unknown function. Examp...

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Duke scientists create airway spheres to study lung diseases

From this single "basal" cell, a small, squat stem cell that divides to replenish the lung lining layer, scientists created 3-D hollow spheres that were lined inside with both ciliary and se...

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Placenta-derived stem cells may help sufferers of lung diseases

An Italian research team, publishing in the current issue of Cell Transplantation (18:4), which is now available on-line without charge at http://www.ingentaconnect.com/content/cog/ct, has found that ...

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Common cold virus efficiently delivers corrected gene to cystic fibrosis cells

Now University of North Carolina at Chapel Hill School of Medicine scientists have found what may be the most efficient way to deliver a corrected gene to lung cells collected from cystic fibrosis pat...

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Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients

According to senior author Naftali Kaminski, M.D., associate professor of medicine, computational biology and pathology, and director of the Dorothy P. and Richard P. Simmons Center for Interstitial L...

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New test can detect both genetic and chromosomal abnormalities in embryos

They told a news briefing at the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam today (Tuesday) that, as a result, they would be able to offer clinical t...

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