For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder. Mendelian disorders, ...
Life Sciences |Researchers aimed to investigate whether the mononuclear cell fraction of human cord blood (HUCBM cells), which contains stem cells, might be useful in hepatic regenerative medicine. Both histological...
Life Sciences |Now a collaborative study from North Carolina State University, The Hamner Institutes for Health Sciences, and the National Institute of Environmental Health Sciences shows that inhaling these nanotub...
Studies and Analyses |Scientists prevented age-related changes in the hearts of mice and preserved heart function by suppressing a form of the PI3K gene, in a study reported in Circulation: Journal of the American Heart As...
Studies and Analyses |The five-year project, part of the NIH Director’s Transformative Program (T-R01), will focus on three types of disease-producing bacteria to determine how dormant subpopulations of these microorganism...
Life Sciences |The discovery was reported in a study posted online Sept. 14 by the Journal of Clinical Investigation. The new research sheds light on what has been a medical mystery - the precise biological reasons ...
Health and Medicine |Those who carry a particular variant of the SERPINA1 gene (also known as alpha-1-antitrypsin or alpha-1-antiprotease) are five times more likely to develop cirrhosis and other liver complications than...
Life Sciences |A diagnosis of Idiopathic Pulmonary Fibrosis is not much better than a death sentence: there is no treatment and the survival rate is less than three years.But researchers at the University o...
Health and Medicine |But researchers at the University of Michigan have discovered that targeting of a novel gene utilizing genetic and pharmacologic strategies was successful in treating pulmonary fibrosis in mice and wi...
Life Sciences |Ciliopathies are a newly emerging group of diseases caused by defects in the function or structure of cellular primary cilia, which are small, cellular appendages of previously unknown function. Examp...
Life Sciences |From this single "basal" cell, a small, squat stem cell that divides to replenish the lung lining layer, scientists created 3-D hollow spheres that were lined inside with both ciliary and se...
Health and Medicine |An Italian research team, publishing in the current issue of Cell Transplantation (18:4), which is now available on-line without charge at http://www.ingentaconnect.com/content/cog/ct, has found that ...
Life Sciences |Now University of North Carolina at Chapel Hill School of Medicine scientists have found what may be the most efficient way to deliver a corrected gene to lung cells collected from cystic fibrosis pat...
Life Sciences |According to senior author Naftali Kaminski, M.D., associate professor of medicine, computational biology and pathology, and director of the Dorothy P. and Richard P. Simmons Center for Interstitial L...
Life Sciences |They told a news briefing at the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam today (Tuesday) that, as a result, they would be able to offer clinical t...
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