New Products – Highlights of COMPAMED 2016

NanEye - The award winning, smallest digital camera in the world, for disposable endoscope. CMOSIS Germany GmbH

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will focus on the innovations from key technologies like microtechnology, nanotechnology, photonics or advanced materials. The joint pavilion in Hall 8a hosts about 50 international exhibitors on 700 sqm of space. The exhibitors will showcase miniaturized components and high-tech electronics, innovative laser technology, functional coatings, smart sensors as well as high-precision structuring, measuring and screening processes that constantly make medical technology products safer, cheaper and more reliable.

Additionally, the COMPAMED HIGH-TECH Forum in hall 8a offers extensive insights into research and development processes of the showcased products, comments on current technology trends and provides information about relevant foreign markets for medical technology. This year, a German-Japanese session will focus on commercial licensing for medical products in Germany and Japan and elaborate on export issues.

Smart sensor technologies enable powerful wearables

Die ACEOS GmbH develops and produces gas sensors for diagnostic and therapeutic use in medical technology, consumer health and lifestyle products. ACEOS announces its new development: ACE-O2, a polymer-based 'cold' oxygen sensor. It is precise and fast, small and light, with low energy consumption, up to the entire range (i.e. 0-100 Vol% O2), which makes it a perfect candidate for use in wearables, cardiorespiratory applications, stress analysis, calculation of metabolic consumption, sports medicine, indirect calorimetry, monitoring of patients and ICU.

CiS Forschungsinstitut für Mikrosensorik GmbH develops technologies for customized optoelectronic, piezoresistive and impedimetric sensors. Among the novelties are optical sensors for measuring the blood flow velocity in the skin. The sensor uses the laser Doppler principle and is manufactured on the MORES technology platform of the research institute. Light sources are embedded directly as bare die into the sensor chip. In addition, CiS for the first time presents a MEMS conductivity sensor based on micro-interdigital structures for measuring the growth of cell cultures, e.g. to run toxicity testing.

Sensirion AG, the expert for safe and reliable medical applications, is presenting its innovative sensors for the measurement and control of gas and liquid flows, differential pressure, humidity and temperature. The SFM3000 platform offers a wide range of mass flow meters for respiratory applications and also includes autoclavable flow sensors. For the first time, the flow sensor range now includes disposable mass flow meters. Furthermore, Sensirion presents the world’s smallest differential pressure sensor, which opens up countless new integration and application possibilities.

The Fraunhofer Institute for Silicon Technology ISIT researches and manufactures components and systems in microelectronics and microsystems technology. The business unit “Medical Sensor Systems” researches on portable multi-parameter analysis systems for point-of-care diagnostics. The business field “Wearables and Printed Electronics” develops new products for sports, medicine, personal safety and automotive applications. Examples are autarkic force sensing shoe inlays for acoustic gait analysis or hybrid electronics systems for body tracking applications.

Micro and nano coatings for high-tech surface solutions

Surfix BV presents its advanced nanocoatings for the micro- and nanotechnology market. The proprietary surface modification technology can be used to locally functionalize complex devices with molecular nanocoatings. Surfix’s advanced nanocoatings enable the generation of patterned surfaces with multiple functionalities on various inorganic and polymeric surfaces and even inside microfluidic channels, leading to devices with improved performance.

SCS – Specialty Coating Systems will be exhibiting Parylene conformal coating services at COMPAMED. SCS Parylene coatings are biocompatible, biostable and offer excellent moisture, chemical and dielectric barrier properties to many medical devices, including stents, catheters, pacemakers, needles and mandrels, and to pharmaceutical containers and applications as well. Ultra-thin and perfectly conformal, Parylene coatings are ideal for advancing medical technologies.

Many medical applications are using the advantage of micro- and nanostructured surfaces. temicon GmbH offers the complete technology range needed for the processing and the serial production of functional surfaces by injection molding or roll imprint. Typical products are nebulizer nozzles with micrometer holes for the generation of aerosols, microstructured titerplates for stem cells differentiation, conic micromembranes for filtering of cells, or anti-bacterial surfaces. In addition, temicon offers injection mold inserts and injection molding service for the production of micro- or nanostructured polymer parts.

Precise microfluidic systems for point-of-care applications

HNP Mikrosysteme GmbH produces micro annular gear pumps. These pumps are ideally used where fast and highly precise dosage is required. Five series guarantee a flow rate from 1 µl/h to 1152 ml/min. mzr-pumps are characterized by low pulse delivery, minimal dead volume, long service life, small dimensions, powerful materials and ease of maintenance. HNPM offers development of OEM pumps, comprehensive application-specific consulting and technical support. Application possibilities are, amongst others, in the field of life science and analytical instrumentation.

Micronit GmbH is a key supplier of microfluidic devices to life sciences and chemistry markets worldwide and has been manufacturing microfluidic components for more than 15 years. These products are used in DNA analysis, as medical tests, as components for analytical instrumentation and space technology. Micronit has extensive experience in micromachining, microfluidics and MEMS and is a dedicated research and development partner for both science and industry.

The highlight exhibit of Fraunhofer ICT-IMM is the CTCelect system, a platform technology for liquid biopsy sample processing and analysis. Its main function is the isolation and single cell enrichment for next-generation sequencing analyses of the individual CTCs. The institute also present the Simplex system, a mobile, autonomously working platform for the point-of-care diagnosis of influenza. With Simplex it is possible to determine not only the infection status of the patient, but also the subtype of the influenza virus. The portfolio is completed by further microfluidic components.

Innovative microelectronics

Through longstanding experience AEMtec GmbH has positioned itself as a reliable partner for the manufacture of products with a high level of integrity and reliability. AEMtec is ISO 13485 certified and offers its customers development and production services for new product integration or re-design for medical devices from class 1 to class 3, such as imaging system applications for daily use in mobile diagnostic and implants. AEMtec provides a wide range of assembly and packaging technologies in cleanroom environment (Wafer Back-End Services, CoB, Flip Chip, SMT) and box-build.

European Sensor Systems specializes in the development of silicon-based modules utilizing micro-electronic technologies. Its prime scope of work is to design, develop and produce customer-specific MEMS modules via standard industrial processes employed for medical, industrial and aerospace applications. ESS's MEMS-based products are: flow systems for gases including oxygen, silicon capacitive pressure sensors for gases and liquids underpinned by ESS's innovative microfabrication process, capacitive accelerometers and signal conditioning electronics.

CorTec GmbH develops and markets innovative neuroprosthetic devices providing a lot of new opportunities for therapy and research. With products for the next generation of neurotherapy CorTec makes it possible to accurately address a multitude of diseases and research issues.

Exceet electronics GmbH is the European specialist with years of experience for industrialized and automated development and manufacturing of high-quality and complex electronic modules, components and systems. In medical technology for example, the company adopts the overall responsibility for the development and manufacturing of medical devices and supports their admission. Exceet electronics is a wholly reliable outsourcing partner and general contractor.

MAZeT GmbH is an electronics design & manufacturing services provider, which is specialized in the market segment of medical electronics, automation technology and industrial electronics with customized, embedded computing solutions and mixed signal ASIC/FPGA design services. MAZeT provides its own products and solutions for applications of spectral and color sensor technology under the brand name JENCOLOR. MAZeT is a DIN ISO 9001:2008 and DIN EN ISO 13485 certified service partner.

Microdul AG is specialized in high-quality microelectronics. The company's three business lines are customized modules, thick-film and mixed-signal low-power ASICs. With ISO 13485, the company's core competence is producing cutting-edge micro miniature modules for medical and industrial applications, such as implants, hearing aids or modules for use in healthcare.

Optiprint AG offers consultation, development and manufacture at its production facility in east Switzerland. Optiprint guarantees Swiss quality and precision. The company offers innovative PCB solutions like high-frequency printed circuit boards, metal-core printed circuit boards, flexible and flex-rigid printed circuit boards, ultra-fine lines and printed circuit boards with ticer foil.

Turck duotec GmbH develops and produces miniaturized electronic components such as LED lighting on ceramic substrates and overmolded sensor modules. By using the new overmolding technology, electronic components are effectively protected from the effects of hot steam sterilization in an autoclave at 134 °C and 2 bar water vapor pressure. The new autoclavable overmolding technology allows precise and miniaturized packaging of sensors and other electronic assemblies using overmolding with plastics materials and thus permitting repeated applications for medical usages.

SMT & HYBRID GmbH is an expert for the development, production and the full service of electronic assemblies and devices. The company responds to the uniqueness of each customer’s product idea or fully developed product with individual electronic services and considers all processes both thoroughly and holistically from series production. The interaction of a sophisticated electronic and mechanical design with coordinated concepts regarding procurement, production, testing and logistics is the key to the technically mature and economic manufacture of a product.

Laser technology and photonics for medical manufacturing

With more than 415 employees and more than 19,500 m² of net floor space the Fraunhofer Institute for Laser Technology ILT is one of the most important development and contract research institutes of its specific field worldwide. The activities cover a wide range of areas such as the development of new laser beam sources and components, precise laser-based metrology, testing technology and industrial laser processes. These include laser cutting, caving, drilling, welding and soldering as well as surface treatment, micro processing and rapid manufacturing.

Micreon GmbH is one of the world’s most prestigious contract manufacturers and technology consultants for micromachining with ultrafast lasers. Ultrafast laser technology has all the advantages necessary for current and future miniaturization applications, with processing resolutions in the sub-micrometer range that are not only smaller, but of higher quality than comparable conventional methods. Micreon is partner for contract manufacturing, research and consulting.

ROFIN-BAASEL Lasertech GmbH & Co. KG offers laser solutions for medical technology, including the StarCut tube family, the high-precision laser cutting systems for tubes and medical implants. In addition, the company presents laser processing systems for high-precision welding, cutting, structuring, drilling and marking.
LithoProf3D is a tool for ultra-precise material processing for additive and subtractive manufacturing offered by Multiphoton Optics GmbH. It allows to perform a large variety of processes which can be easily integrated into conventional process chains. The flexible software package is designed for the LithoProf3D as well as stand-alone software for GCode compatible manufacturing machines. It meets the most demanding requirements for standard and sophisticated work flows in the exciting world of high-precision 3D printing.

High-quality lenses, optical systems and components

The BERLINER GLAS GROUP is one of the world’s leading providers of optical key components, assemblies and systems as well as high-quality refined technical glass and optical bonded touch systems. BERLINER GLAS develops, produces and integrates optics, mechanics and electronics into innovative system solutions for its customers. As a classic OEM partner, BERLINER GLAS supplies innovative companies from the medical technology and life science market who are a cut above the competition thanks to the quality and functionality of their products.

CMOSIS Germany GmbH presents NanEye, the world’s smallest digital image sensor with only 1mm side length and integrated optics. With the NanEye image sensor visualization can be introduced to virtually any micro-invasive procedure. CMOSIS‘ main expertise in medical imaging is centered around endoscopy devices and bringing visualization to routine medical procedures, in many cases for the first time.

FISBA AG is a worldwide leading supplier of customized optical components, microsystems and systems. You benefit from our many years of counseling, development and manufacturing and innovative process- and manufacturing technologies. Products include microcams, microlenses, and laser modules. FISBA also offers services like product development, optic design, high-quality coatings, or assembly.

IMT Masken und Teilungen AG presents cost-effective glass components for biophotonics and medical applications. IMT develops and produces large volumes of consumables, custom-made microfluidic devices, optical components and sensors in glass and quartz. IMT’s capabilities include structured metallic and dielectric coatings, etching of channels and nanopatterns, integration of on-chip electrodes, waveguides, optical filters and biocompatible materials for applications such as sequencing, lab-on-a-chip, organ-on-a-chip, single cell detection & analysis or HTS.

Mikrop AG is the leading source for Swiss precision miniature optics serving all high-tech markets. For 35 years the company has developed, manufactured and mounted highly complex, miniaturized optical components and sub-assemblies. Today Mikrop is one of only a few companies worldwide who are able to manufacture serial high-precision lenses in reliable top quality and starting at diameters of just 0.3mm and up to 15mm.

Volpi AG develops, industrializes and manufactures optoelectronic module solutions for in vitro diagnostics and life science research (fluorescence, reflectometry, chemiluminescence, calorimetry, spectroscopy). Applications include modules for PCR, next-generation sequencing, immunoassay systems and clinical chemistry analyzers.
Based in the USA and Switzerland, certified ISO 13485, Volpi provides comprehensive systems engineering combined with lean manufacturing throughout the product life cycle.

Zünd Precision Optics presents micro planar optical single components and planar optical kitting systems at COMPAMED. Zünd produces and distributes uncoated or coated planar optical single components and planar optical assemblies in dimensions of 0.2mm up to 50.0mm. The company’ s support begins with the design, development of prototypes and extends to the execution of production from 50 to 20,000 units and more.

The Optoelectronic Systems business unit of JENOPTIK AG is a provider of integrated opto-electronic system solutions. The business unit has competencies in development of optics, electronics and software, and owns manufacturing technologies for producing polymer-based optical and electronic components and modules as well as assembly technologies for complete devices.

Ultraprecise microstructures, parts and components

CG.TEC Injection is a leading expert in high-precision injection-molding and manufactures miniature parts and microcomponents out of polymers. The company designs parts for manufacture, develops precision tooling and automates the production. The scope of products ranges from small equipment to disposables for different applications: diagnostics, dentistry, surgery, microfluidics, and many more.

The Austrian branch of Microsystems UK Ltd is specialist in medical, biotech and optical micro-molding solutions including molds, plastic parts and complete systems for drug delivery, medical diagnostics, surgery and inhalation. Further capabilities include ultra-precision multi-cavity molds and nano-structuring, manufactured in high and medium quantities to suit the customers’ specific requirements.

At COMPAMED RKT Rodinger Kunststoff-Technik GmbH presents itself as a partner for precision mold making, precision injection molding, 2 and 3 shot components, micro parts, microfluidic parts, part assembly, cleanroom production, mold engineering, and validation.
Ultraprecision products made by KUGLER GmbH have been used in the medical industry, where absolute reliability is imperative, right from the start. Precision parts are used in the manufacture of endoscopes, polygon scanners for the examination and treatment of eye defects with lasers, micro-focusing mirrors and laser systems. At the COMPAMED 2016, KUGLER presents optics and laser system components, microstructures, microfluidic parts, embossing and forming tools as well as components machined on ultraprecision machines such as the MICROMASTER, which have been self-developed for own job shop and are also available for customers.

Microsystems for life-science applications

Electromag SA is specialized in the design, production and sales of high-performance miniature brushless motors for the medical industry. The company has developed a significant experience in the field of medical respirators as well as for other medical devices that require high-speed, low noise and reliable motors.

Hahn-Schickard is well known for industry-oriented research, development and fabrication in microsystems technologies. In trustworthy cooperation with industry, Hahn-Schickard develops innovative products and technologies in research fields with a strong future impact such as the internet of things, sustainable mobility, environmental and natural resources, healthcare as well as information and communication technologies. Hahn-Schickard offers production of small and medium-sized series as well as transition into mass production.

The Fraunhofer Institute for Electronic Nano Systems ENAS focusses on smart systems integration by using micro & nano technologies. The Fraunhofer ENAS operates in three business areas: “Micro and Nano Systes”, “Green and Wireless Systems” and “Micro- and Nanoelectronics / Back-end of Line”.

PI (Physik Instrumente GmbH & Co. KG) is a leading manufacturer of nano and micropositioning systems. PI can rely on a broad range of drive solutions for applications in research, diagnostics and therapy. This means that endoscopy, for example, can benefit from piezo-motorized and magnetic miniature drives. In addition, PI offers piezoceramic elements that can be used in sensory and actuator applications, for example, in flow meters or as components in pump and metering technology. PI products therefore meet the high requirements on reliability and lifetime.

Hittech Group BV is a system supplier and partner for OEM companies. The group is specialized in the development and manufacture of components and devices in the following segments: medical technology, microelectronics and semiconductor manufacturing, laboratory and analysis equipment and packaging machines.

Steinmeyer Mechatronik GmbH (formerly known as Feinmess Dresden GmbH) is part of the international Steinmeyer group. As the competence center for positioning solutions and mechatronic systems, Steinmeyer Mechatronik offers innovative products and competent advice for specific positioning tasks and supplies a broad portfolio of different positioning solutions. Already in the design phase the company pays attention to a competitive price-performance ratio, whereas quality is understood.

Research, development and manufacturing services

CSEM Centre Suisse d'Electronique et de Microtechnique SA with more than 400 employees is a Swiss non-profit R&D organization specialized in microtechnology. It offers tailored, innovative solutions based on its technological excellence. CSEM is highly active in the medtech domain. As an example, CSEM develops wearables that monitor physiological parameters non-invasively. CSEM also provides technologies for diagnosis and therapy covering system design, sensing and actuation, communication or power supply as well as bio-compatible packaging.

ECR AG is a full service provider that develops, produces and assembles MedTec devices according to ISO13485. The extensive services include hardware and software development as well as mechanical design. The basic life-cycle-management tool Polarion offers the opportunity for an easy joint development with customers due to cloud technology. The PCBA is manufactured and the device finally assembled at ECR’s facilities.

For more than 15 years the Fraunhofer Institute for Reliability and Microintegration IZM has served the medical industry as a one-stop-shop solution provider with its technology portfolio adapted to heart pace makers, to retinal implants, to lab-on-chip platforms, to neuroprosthetic devices and hearing aids. Services include electronic packaging and reliability assessments for miniaturized medical devices and implants, lab-on-substrate technologies for POCT, and improved functionalities for neuronal interfaces and intelligent prostheses.

Statice Innovation introduces an electro-spinning process for innovative medical devices at COMPAMED. The electro-spinning process offers a large number of groundbreaking applications in generative medicine by producing and conditioning functional scaffolds. Thanks to its long-term experience in R&D projects with universities in various industries and its collaboration on two European projects, Statice is able to produce scaffolds in tube shape with different diameters with its own machine.

Further innovations for medical device technology

The benefits of using RFID technology in the medical and healthcare sector are immense: huge time savings, cost reduction through optimized processes and improvements in quality management are just some of them. Microsensys GmbH offers established RFID system solutions for applications such as unique part tagging, specimen management, inventory, pressure and temperature monitoring as well as special security solutions. At COMPAMED microsensys shows as world first an RFID sensor data logger for continuous temperature monitoring during steam sterilization at +136 °C and 2 bar.

The core competency of Rohrer AG is developing and manufacturing packaging solutions from flexible foils. Rohrer accompanies its customers from the initial idea to final realization with the goal of producing customized tools and machines. The company’s expertise lies in creating GMP-compatible solutions for the pharmaceutical and the medical industries in full compliance with respective laws and regulations and anticipation of upcoming regulatory changes. Since its foundation in 1962 Rohrer AG has transformed itself into a technology leader with its proprietary processes and products.

Efficient network for initial business contact

IVAM Microtechnology Network is an international association with members in the fields of microtechnology, nanotechnology, advanced materials and photonics. IVAM supports mainly small and medium-sized companies in bringing innovative technologies and products to market and thus securing advantages in international competition. Since 1995 IVAM has been supporting companies and institutions from all around the world. The central mission of the association is to create synergies and to support its members in exchanging knowledge, initiating joint projects and networking with each other and potential customers.

Further information and an exhibitor overview including contact data can be found at http://ivam.de/compamed16.
Images for editorial use (including reference) can be downloaded at
https://web.ivam.de/dl/COMPAMED_IVAM_press_images.zip

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