The invention allows a selective extraction and analysis of cells from defined positions within natural or artificial three-dimensional structures without destroying the cell culture medium. This is achieved by a cell reactor having an upper part and lower part which are detachably connected together as well as inflow and outflow openings for liquid or gaseous nutrient medium. The flow through the cell culture with cell medium can be carried out both apically and basally. Furthermore, the reactor has a layer system with layer basket for receiving the cell culture carriers in the form of layers and positioning them along a fixing ring. The layers can have different geometric shapes and can be made out of different materials and are also reus-able.
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