Adhesin with high chitin-binding specificity
The new recombinant protein is based on the recently identified Cea1 adhesin from the yeast Pichia pastoris. It provides a high specificity for non-reducing N-acetylglucosamine (GlcNAc) ends of non-crystalline chitin, chitin-like polymers, or N-linked glycans, while recognition of glucose, glucosamine, or N-acetylneuraminic acid (Neu5Ac) is subordinate.
The technology therefore enables highly specific binding of chitin or chitin-like polymers in the context of biomedical or biotechnological applications.
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