Stomach MRI images combined with functional fMRI of the brain activity have provided scientists new insight into how the brain listens to the stomach during eating
Stomach MRI images combined with functional fMRI of the brain activity have provided scientists new insight into how the brain listens to the stomach during eating. Research from Wageningen University in the Netherlands shows - for the first time - real time data of the brain, the stomach, and people's feelings of satiety measured simultaneously during a meal, in a study to be reported this week at the annual meeting of the Society for the Study of Ingestive Behavior, held in Porto, Portugal. The researchers collected data from 19 participants during two separate sessions with different consumption procedures and found that a simple change like drinking more water can alter messages from the stomach interpreted as fullness by the brain. This new research approach can be used to investigate the interplay between satiety feelings, volume of the stomach and activity in the brain.
In the experiment, participants drank a milk-shake on an empty stomach, which was followed by a small (50 mL) or large glass of water (350 mL). MRI images were used to see how the different amounts of water affected stretching of the stomach: the large glass of water doubled the stomach content compared to the small glass. Together with this larger volume subjects reported to have less hunger and felt fuller.
This novel approach - combining information obtained simultaneously from MRI images of the stomach, feelings reported by the subjects, and brain scans - can offer new insights which would otherwise have been unknown, for example that activation in a brain area called the mid-temporal gyrus seems is in some way influenced by the increased water load in this experiment. The Wageningen University scientists developed the combined MRI method as part of the European Nudge-it research project, which seeks to discover simple changes that promote healthier eating. They will use it to search for a brain signature that leads people to decide to stop eating, to determine how strategies like water with a meal can be effective at feeling fuller sooner.
"Combining these types of measurements is difficult, because MRI scanners are usually set-up to perform only one type of scan. We've been able to very quickly switch the scanner from one functionality to another to do this type of research" says Guido Camps, lead author of the study. "In conclusion, we've found that simply adding water increases stomach distension, curbs appetite in the short term and increases regional brain activity."
Activation in the insula is increased when the stomach is distended more.
The same subject with either the small (left) or large volume of water (right) in the stomach (delineated in red).
Research: "Just add water: how water affects gastric distension, appetite and brain activity"
G CAMPS, R VEIT, M MARS, C DE GRAAF, P SMEETS
Melissa Szkodzinska | EurekAlert!
Illinois researchers researchers find tweeting in cities lower than expected
21.02.2018 | University of Illinois College of Engineering
Polluted air may pollute our morality
08.02.2018 | Association for Psychological Science
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...
Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...
On 15 March, the AWI research aeroplane Polar 5 will depart for Greenland. Concentrating on the furthest northeast region of the island, an international team...
The world’s second-largest ice shelf was the destination for a Polarstern expedition that ended in Punta Arenas, Chile on 14th March 2018. Oceanographers from...
At the 2018 ILA Berlin Air Show from April 25–29, the Fraunhofer Institute for Laser Technology ILT is showcasing extreme high-speed Laser Material Deposition (EHLA): A video documents how for metal components that are highly loaded, EHLA has already proved itself as an alternative to hard chrome plating, which is now allowed only under special conditions.
When the EU restricted the use of hexavalent chromium compounds to special applications requiring authorization, the move prompted a rethink in the surface...
19.03.2018 | Event News
16.03.2018 | Event News
13.03.2018 | Event News
19.03.2018 | Event News
19.03.2018 | Information Technology
19.03.2018 | Interdisciplinary Research