Researchers at Aalto University, Finland, have developed a biosensor that enables creating a range of new easy-to-use health tests similar to home pregnancy tests. The plasmonic biosensor can detect diseased exosomes even by the naked eye. Exosomes, important indicators of health conditions, are cell-derived vesicles that are present in blood and urine.
A rapid analysis by biosensors helps recognize inflammatory bowel diseases, cancer and other diseases rapidly and start relevant treatments in time. In addition to using discovery in biomedicine, industry may use advanced applications in energy.
Researchers created a new biosensor by depositing plasmonic metaparticles on a black, physical body that absorbs all incident electromagnetic radiation. A plasmon is a quantum of plasma oscillation. Plasmonic materials have been used for making objects invisible in scientific tests. They efficiently reflect and absorb light. Plasmonic materials are based on the effective polarizabilities of metallic nanostructures.
"It is extraordinary that we can detect diseased exosomes by the naked eye. The conventional plasmonic biosensors are able to detect analytes solely at a molecular level. So far, the naked-eye detection of biosamples has been either rarely considered or unsuccessful", says Professor Mady Elbahri from Aalto University.
Plasmonic dipoles are famous for their strong scattering and absorption. Dr. Shahin Homaeigohar and Moheb Abdealziz from Aalto University explain that the research group has succeeded in demonstrating the as-yet unknown specular reflection and the Brewster effect of ultrafine plasmonic dipoles on a black body host.
"We exploited it as the basis of new design rules to differentiate diseased human serum exosomes from healthy ones in a simple manner with no need to any specialized equipment", says Dr. Abdou Elsharawy from the University of Kiel.
The novel approach enables a simple and cost-effective design of a perfect colored absorber and creation of vivid interference plasmonic colors.
According to Elbahri, there is no need to use of sophisticated fabrication and patterning methods. It enables naked-eye environmental and bulk biodetection of samples with a very minor change of molecular polarizability of even 0.001%.
The study was published in Advanced Materials.
Mady Elbahri | EurekAlert!
Indications of Psychosis Appear in Cortical Folding
26.04.2018 | Universität Basel
GLUT5 fluorescent probe fingerprints cancer cells
20.04.2018 | Michigan Technological University
Magnetic resonance imaging, or MRI, is a widely used medical tool for taking pictures of the insides of our body. One way to make MRI scans easier to read is...
At the Hannover Messe 2018, the Bundesanstalt für Materialforschung und-prüfung (BAM) will show how, in the future, astronauts could produce their own tools or spare parts in zero gravity using 3D printing. This will reduce, weight and transport costs for space missions. Visitors can experience the innovative additive manufacturing process live at the fair.
Powder-based additive manufacturing in zero gravity is the name of the project in which a component is produced by applying metallic powder layers and then...
Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.
Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
13.04.2018 | Event News
12.04.2018 | Event News
09.04.2018 | Event News
26.04.2018 | Power and Electrical Engineering
26.04.2018 | Life Sciences
26.04.2018 | Power and Electrical Engineering