Special section in SPIE Journal of Biomedical Optics commemorates 25 years of OCT and takes a look into the future of the noninvasive imaging modality
Optical coherence tomography (OCT) has revolutionized ophthalmology in the 25 years since the technology's inception, by providing the capability to noninvasively measure and create 3D images at the microscopic scale of tissues inside the body. Now increasingly used in cardiology, dermatology, and other medical specialties, new opportunities continue to emerge across a wide range of fields beyond medicine and biology.
Each B-scan consists of PA-scans acquired sequentially along the x-direction. An OCT volume consists of QB-scan images acquired along the y-direction. Pixels along the y-direction from N adjacent B-scans were used to determine the frequency components. (Fig. 1 from 10.1117/1.JBO.22.12.121710)
Credit: Jordi L. Tremoleda; Karl Alvarez; Abdirahman Aden; Robert Donnan; Adina T. Michael-Titus; Peter H. Tomlins
Now the dominant diagnostic tool for conditions such as macular degeneration and glaucoma, OCT technology continues to offer potential in areas from fundamental research to clinical applications.
A special section on OCT published by SPIE, the international society for optics and photonics, in the December issue of the Journal of Biomedical Optics (JBO) provides an expert perspective on applications in medicine and biology, particularly those outside ophthalmology. Guest editors are David Sampson (University of Surrey), Peter Andersen (Technical University of Denmark), Ton van Leeuwen (Academisch Medisch Centrum), and Ruikang (Ricky) Wang (University of Washington).
The special section illustrates how, as the technology has matured and some applications have reduced in cost, fresh opportunities pave the way for a new generation of OCT technology translators. OCT remains true to the spirit of the broader field of biophotonics itself, the guest editors noted, with the focus on practical engineering to tackle practical challenges. OCT as a research topic is vibrant and robust, with many new opportunities waiting in the wings for clinical and commercial applications.
Among topics covered in the section's 20 papers are:
The special section also includes a historical account of the life and work of a pioneer of OCT, Adolf Fercher, who died in March 2017, written by his close colleague Christoph Hitzenberger (Medical University of Vienna).
Brian Pogue, Professor of Engineering at Thayer School of Engineering at Dartmouth, is the editor-in-chief of the Journal of Biomedical Optics. The journal is published in print and digitally by SPIE in the SPIE Digital Library, which contains more than 460,000 articles from SPIE journals, proceedings, and books, with approximately 18,000 new research papers added each year. The journal will become fully open access on 1 January 2019.
SPIE is the international society for optics and photonics, an educational not-for-profit organization founded in 1955 to advance light-based science, engineering, and technology. The Society serves nearly 264,000 constituents from approximately 166 countries, offering conferences and their published proceedings, continuing education, books, journals, and the SPIE Digital Library. In 2017, SPIE provided more than $4 million in support of education and outreach programs. http://www.
Kevin Probasco | EurekAlert!
GLUT5 fluorescent probe fingerprints cancer cells
20.04.2018 | Michigan Technological University
Scientists re-create brain neurons to study obesity and personalize treatment
20.04.2018 | Cedars-Sinai Medical Center
Physicists at the Laboratory for Attosecond Physics, which is jointly run by Ludwig-Maximilians-Universität and the Max Planck Institute of Quantum Optics, have developed a high-power laser system that generates ultrashort pulses of light covering a large share of the mid-infrared spectrum. The researchers envisage a wide range of applications for the technology – in the early diagnosis of cancer, for instance.
Molecules are the building blocks of life. Like all other organisms, we are made of them. They control our biorhythm, and they can also reflect our state of...
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
13.04.2018 | Event News
12.04.2018 | Event News
09.04.2018 | Event News
23.04.2018 | Physics and Astronomy
23.04.2018 | Physics and Astronomy
23.04.2018 | Trade Fair News