People in there 80s and 90s are more likely to develop acute coronary syndrome than their younger counterparts. Despite this, they receive less therapy and diagnostic procedures. A doctoral thesis at Sahlgrenska Academy has explored the topic.
Previous studies have shown that older patients are less likely to receive the most evidence-based, recommended treatment for acute coronary syndrome. Regarding the elderly, quality and quantity of the underlying scientific evidence is limited.
Berglind Libungan, PhD Student, University of Gothenburg
University of Gothenburg
A number of recent studies by researchers at Sahlgrenska Academy have included more than 45,000 elderly cardiac patients. Presented in Dr. Berglind Libungan's doctoral thesis, the studies found that treatment of patients with symptoms of acute coronary syndrome, to some extent, is age-related.
• Although patients with chest pain in their 80s and 90s are more likely to have a final diagnosis of acute coronary syndrome, they do less angiograms, echocardiograms and receive less medical therapy compared with their younger counterparts. However, there was not a delay to hospitalization or therapy when compared to younger patients.
"I presume that older patients receive less evidence-based treatment because the treating physician feels that the risks outweigh the benefits," Dr. Libungan says.
• The risk for death, among older patients with myocardial infarction who are treated with medical therapy, is higher than among patients who do an intervention, coronary angioplasty.
"Given the major differences between various patient groups, this finding does not mean that interventions are automatically better," Dr. Libungan says. “Patients who are treated with medication alone are usually older and in poorer health. Additional clinical research is needed to determine the strategy that works best for older patients.”
• The number of elderly Swedes with myocardial infarction treated with balloon angioplasty has increased over the past decade. Even though they are generally older and sicker, the risk for complications has not increased.
"The evidence suggests that more elderly patients could be offered balloon angioplasty," Dr. Libungan says.
Higher mortality rate
The new studies have also found that elderly patients who suffer cardiac arrest have a higher mortality rate which increases with age. The survival rate is 6.6% among 70-80 year-olds, 4.4% among 80-90 year-olds and 2.3% among those older than 90.
Mr. Libungan will defend his thesis, "Acute coronary syndrome and cardiac arrest in the elderly" on May 28.
Link to thesis: http://hdl.handle.net/2077/38347
Berglind Libungan, PhD Student, Sahlgrenska Academy, University of Gothenburg
Supervisor: Per Albertsson
Henrik Axlid | idw - Informationsdienst Wissenschaft
Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences
What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
24.03.2017 | Materials Sciences
24.03.2017 | Physics and Astronomy
24.03.2017 | Physics and Astronomy