An Indiana University study has revealed that there may be a greater connection between mussels and muscles than previously thought.
The study, by kinesiology professor Timothy Mickleborough at the IU School of Public Health-Bloomington, found that taking a pre-exercise supplement of the omega-3 PCSO-524, a marine oil lipid derived from the New Zealand green-lipped mussel, has significant positive effects on post-exercise muscle damage.
The pharmaceutical name of the supplement is Lyprinol, or Omega XL in the United States, and it has previously been used to effectively reduce the effects of osteoarthritis, rheumatoid arthritis, inflammatory bowel disease and exercise-induced asthma. Pharmalink International LTD, which funded the study, develops it.
Mickleborough said his initial study of this particular marine oil supplement led him to further test its healing properties on other parts of the body.
"I've worked with Pharmalink before when they approached me to do a study with this particular oil and its effects on exercise-induced asthma and respiratory inflammation," Mickleborough said. "I thought if it can be used as an anti-inflammatory for lungs, perhaps it could reverse muscle inflammation as well."
For the study, lead author Mickleborough and his colleagues tested 32 "untrained male subjects" -- men who exercise less than three times a week for less than 30 minutes at a time -- who would elicit a greater muscle response than an athlete who is used to regular muscle damage. The subjects were randomly given either the marine oil supplement or a placebo for 26 days before a muscle-damaging exercise session and for 96 hours afterwards.
The exercise session consisted of running at fairly high intensity for 20 minutes downhill on a treadmill. The body's reaction to the muscle-damaging exercise regimen was tested immediately, and at 24, 48, 72 and 96 hours post-workout.
The men who were given the PCSO-524 marine oil supplement exhibited less muscle soreness, less muscle pain, less strength loss, less fatigue and even less inflammatory proteins evident in their bloodstreams. Overall, they experienced less bodily stress after their workout in comparison to the subjects who were given the placebo.
For people who are looking to start exercising again, or even for those who engage in intense workouts regularly, this discovery can have a variety of positive effects on how their bodies react to muscle damage, Mickleborough said.
"It might have positive implications for triathletes if they're doing several different types of exercises, and it could potentially help diminish soreness in multisport, recreational athletes as well," he said. "Essentially, for anyone who is engaging in unaccustomed exercise, it's a nice product."
Mickleborough's study "The effects PCSO-524®, a patented marine oil lipid and omega-3 PUFA blend derived from the New Zealand green lipped mussel (Perna canaliculus), on indirect markers of muscle damage and inflammation after muscle damaging exercise in untrained men: a randomized, placebo controlled trial" is featured in the Feb. 2015 issue of the Journal of the International Society of Sports Nutrition.
Co-authors include Robert Chapman, assistant professor in the School of Public Health-Bloomington; Jacob Sinex, doctoral candidate in the School of Public Health-Bloomington; Molly Hirt, IU School of Medicine student; and David Platt, doctoral candidate at the University of Notre Dame.
The study was supported by a grant from Pharmalink International LTD, which manufactures and owns PCSO-524. The funder had no role in study design, data collection and analysis, in writing the journal article, or the decision to publish.
For a copy of the paper or to speak with Mickleborough, contact Milana Katic at firstname.lastname@example.org or 812-855-0084.
Visual and Digital Media Specialist
Milana Katic | newswise
Inflammation Triggers Unsustainable Immune Response to Chronic Viral Infection
24.10.2016 | Universität Basel
Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
25.10.2016 | Earth Sciences
25.10.2016 | Power and Electrical Engineering
25.10.2016 | Process Engineering