Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

High speed video recording precisely measures blood cell velocity

15.11.2017

Scientists from ITMO University created a high-speed video capillaroscopy system that enables direct measurement of red blood cell velocity. Coupled with sophisticated software, the system can raise the bar on the accuracy of vascular condition assessment. Such a system can come in useful for monitoring how efficient certain therapies are. The results of the research were published in Optics and Lasers in Engineering.

Capillaroscopy systems are commonly used either to determine the shape and size of a single capillary or to examine some specific part of a capillary network. Geometric patterns that emerge from capillary structures, as well as blood cell velocity, can reflect the condition of the entire vascular system. Although blood cell velocity is among crucial diagnostic parameters, so far its direct and precise measurement was not an easy task.


This is a picture of nailfold capillary network obtained by new system.

Credit: Provided by leading author IgorGurov

In the study, researchers from ITMO University applied high speed video recording of red blood cells in the capillary to measure blood flow velocity. The system relies on the combination of optical equipment with specially designed data processing software.

A microscope coupled with a high speed video camera captures the image of capillaries. The frame sequence is then processed in order to restore the capillaries' shape and configuration as well as to determine the distance that blood cells cover per time unit. Besides being useful for diagnostics, such data may help to assess whether a certain therapy is efficient or not.

"In addition to shape and diameter of each capillary, we can determine how fast red blood cells flow through each capillary in observed capillary net," comments Igor Gurov, lead author and head of the Center For Computational Optics, Photonics and Imaging at ITMO University. "Although relatively simple, our device is capable of providing reliable data that can be extremely useful for disease patterns recognition. What is more, such a diagnostic procedure is absolutely painless, safe and comfortable for patients."

Retrieving blood flow velocity data is of paramount importance when it comes to such diseases as diabetes or coronary heart disease. "Flow velocity is a primary factor in estimating the condition of any tissue by its blood supply. For instance, in diabetes the circulation speed may alter even though blood vessels generally appear to be normal. Our main task now is to use the system to address socially significant diseases. In particular, the system can be an effective tool for studying what happens in blood vessels during coronary heart disease and how drugs affect blood flow recovery," explains one of the authors Nikita Margariants.

By and large, other methods of measuring blood flow velocity cannot provide highly accurate data and do not allow for long-term measurements. "There are alternative devices that can only give a rough average estimate of blood cell velocity," comments Mikhail Volkov, researcher at the Center For Computational Optics, Photonics and Imaging.

The authors emphasize that the development of image recording and processing facilities will significantly expand the capabilities of the new system. "As new video cameras, exchange buses and software appear, this method will become better and more accurate. Time is on our side," points out Mikhail Volkov.

###

Reference:

"High-speed video capillaroscopy method for imaging and evaluation of moving red blood cells"

I. Gurov, M. Volkov, N. Margaryants et al.

Optics and Lasers in Engineering Sep. 19, 2017 http://www.sciencedirect.com/science/article/pii/S0143816617304578#fig0001

Media Contact

Dmitry Malkov
dvmalkov@corp.ifmo.ru
7-953-377-5508

 @spbifmo_en

http://en.ifmo.ru/ 

Dmitry Malkov | EurekAlert!

More articles from Health and Medicine:

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Research reveals how order first appears in liquid crystals

23.05.2018 | Life Sciences

Space-like gravity weakens biochemical signals in muscle formation

23.05.2018 | Life Sciences

NIST puts the optical microscope under the microscope to achieve atomic accuracy

23.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>