Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Diabetes medication can reduce food intake

29.09.2015

Many studies have focused on how much we eat when we are hungry, but sometimes we eat just to feel better. A new dissertation at Sahlgrenska Academy shows that medication used for type-2 diabetes wich mimics the gut-brain hormone glucagon-like peptide-1, can affect the brain’s reward system and reduce the intake of food.

Obesity and overweight have become a major global problem and can increase the risk of developing cardiovascular diseases and type-2 diabetes, among other problems.


Rozita Anderberg, Researcher at Sahlgrenska Academy

University of Gothenburg

Some high-calorie food can affect the brain in the same way as addictive substances like drugs and alcohol. When we eat, a feeling of well-being is created through the release of dopamine in the brain’s reward center. Overconsumption is considered to be due in part to an imbalance in this system and there is great need for effective new medicines to combat overweight.

Decrease in appetite
Recently, type-2 diabetes has begun to be treated with medications that resemble the body’s own hormone GLP-1, such as Byetta and Victoza. The hormone GLP-1 is produced naturally, both in the intestines and in the brain. After every meal, the levels of GLP-1 in the blood increase, which lead to an increase in insulin production and a decrease in appetite.

Reduce alcohol intake
A new study on rats at Sahlgrenska Academy at the University of Gothenburg shows that hormone-like medication used for type-2 diabetes can affect the brain’s reward system and reduce the need for food intake.

A follow-up study showed that this substance can also reduce alcohol intake.

“Later, we discovered that the same medication can stimulate production of interleukin 6 and interleukin 1, two important hormones that play a major role in our immune system, in the areas of the brain that control appetite. The results are increasing our understanding of how these medications can affect the brain,” says Rozita Anderberg, Researcher at Sahlgrenska Academy.

Potential new treatment
Medications resembling GLP-1 have become a potential new treatment for obesity and these findings can be of major clinical significance.

“Our data can make an important contribution to the understanding of these mechanisms,” says Rozita Anderberg, Researcher at Sahlgrenska Academy.

For additional information, feel free to contact:
Rozita Anderberg, Researcher at Sahlgrenska Academy
+46 761 64 76 66
rozita.anderberg@neuro.gu.se

Weitere Informationen:

http://sahlgrenska.gu.se/english/research/news-article//diabetes-medication-can-...

Calle Björned | idw - Informationsdienst Wissenschaft

More articles from Health and Medicine:

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

nachricht The gut microbiota plays a key role in treatment with classic diabetes medication
01.06.2017 | University of Gothenburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>