Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Diabetes medication can reduce food intake

29.09.2015

Many studies have focused on how much we eat when we are hungry, but sometimes we eat just to feel better. A new dissertation at Sahlgrenska Academy shows that medication used for type-2 diabetes wich mimics the gut-brain hormone glucagon-like peptide-1, can affect the brain’s reward system and reduce the intake of food.

Obesity and overweight have become a major global problem and can increase the risk of developing cardiovascular diseases and type-2 diabetes, among other problems.


Rozita Anderberg, Researcher at Sahlgrenska Academy

University of Gothenburg

Some high-calorie food can affect the brain in the same way as addictive substances like drugs and alcohol. When we eat, a feeling of well-being is created through the release of dopamine in the brain’s reward center. Overconsumption is considered to be due in part to an imbalance in this system and there is great need for effective new medicines to combat overweight.

Decrease in appetite
Recently, type-2 diabetes has begun to be treated with medications that resemble the body’s own hormone GLP-1, such as Byetta and Victoza. The hormone GLP-1 is produced naturally, both in the intestines and in the brain. After every meal, the levels of GLP-1 in the blood increase, which lead to an increase in insulin production and a decrease in appetite.

Reduce alcohol intake
A new study on rats at Sahlgrenska Academy at the University of Gothenburg shows that hormone-like medication used for type-2 diabetes can affect the brain’s reward system and reduce the need for food intake.

A follow-up study showed that this substance can also reduce alcohol intake.

“Later, we discovered that the same medication can stimulate production of interleukin 6 and interleukin 1, two important hormones that play a major role in our immune system, in the areas of the brain that control appetite. The results are increasing our understanding of how these medications can affect the brain,” says Rozita Anderberg, Researcher at Sahlgrenska Academy.

Potential new treatment
Medications resembling GLP-1 have become a potential new treatment for obesity and these findings can be of major clinical significance.

“Our data can make an important contribution to the understanding of these mechanisms,” says Rozita Anderberg, Researcher at Sahlgrenska Academy.

For additional information, feel free to contact:
Rozita Anderberg, Researcher at Sahlgrenska Academy
+46 761 64 76 66
rozita.anderberg@neuro.gu.se

Weitere Informationen:

http://sahlgrenska.gu.se/english/research/news-article//diabetes-medication-can-...

Calle Björned | idw - Informationsdienst Wissenschaft

More articles from Health and Medicine:

nachricht Satellites, airport visibility readings shed light on troops' exposure to air pollution
09.12.2016 | Veterans Affairs Research Communications

nachricht Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>