People who are exposed to higher levels of cadmium have an increased risk of osteoporosis and fractures. Cadmium also affects the kidneys. A doctoral thesis at Sahlgrenska Academy explored this issue in a study of over 900 older men.
We are exposed to low levels of the heavy metal cadmium, daily. This occurs primarily through food, but smokers are also exposed from cigarette smoke. Cadmium in food and cigarette smoke is absorbed and stored by the body, primarily the kidneys.
It has long been known that exposure to high levels of cadmium can cause severe damage to the skeleton and the kidneys, but the effects of low levels have not been studied as thoroughly.
900 older men
In her thesis, Maria Wallin, MD and PhD student at Sahlgrenska Academy, University of Gothenburg, studied over 900 older men.
“Those with higher levels of cadmium in their urine had lower bone mineral density and an increased risk for future fractures. The increased fracture risk applied to osteoporosis related fractures of the hip, pelvis, forearm and shoulder,” says Maria Wallin.
In another study, the effects of cadmium on the kidneys of 109 healthy kidney donors were examined.
“In this study, we had access to biopsy material from the kidneys, which is unique as normally you are unable to measure cadmium levels in kidneys. The results showed that persons with higher cadmium exposure had an increased excretion of calcium in their urine, which could be due to effects on the skeleton or on the kidneys. These persons also had increased excretion of small proteins in their urine,” says Maria Wallin.
Must be reduced
The studies indicate that cadmium can affect the skeleton and maybe also the kidneys, at the low levels found in the Swedish general population.
“The spread of cadmium in the environment must be reduced,” believes Maria Wallin.
Cadmium is a heavy metal that occurs in our environment, both naturally and as a contaminant resulting from agricultural and industrial activities. Cadmium can be found in phosphate fertilizers, but is also spread to agricultural soil by air deposition. Many plants easily absorb cadmium from the soil, which causes cadmium to end up in our crops and tobacco. For the general population, food and cigarette smoking are the two main sources of cadmium.
Link to the thesis Cadmium, kidney and bone: https://gupea.ub.gu.se/handle/2077/39550
Maria Wallin, MD and PhD student at Sahlgrenska Academy
Calle Björned | idw - Informationsdienst Wissenschaft
'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS
New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
19.02.2018 | Materials Sciences
19.02.2018 | Materials Sciences
19.02.2018 | Life Sciences