Due to their nanoscale dimensions and sensitivity to light, quantum dots are being used for a number of bioimaging applications including in vivo imaging of tumor cells, detection of biomolecules, and measurement of pH changes.
When quantum dots are introduced in biological media, proteins surround the nanoparticles and form a corona. The formation of the protein corona changes the sensitivity of the quantum dots to light.
Using the cadmium selenide quantum dot, researchers at Syracuse University collaborated to understand how protein corona forms and what is different about the quantum dot before and after the formation of the corona.
Research performed by Professor Shikha Nangia, in the Department of Biomedical and Chemical Engineering, and Professor Ari Chakraborty, in the Department of Chemistry, resulted in the development of a novel multilevel computational approach.
This method combines the strengths of quantum mechanics, molecular mechanics, classical molecular dynamics, and Monte Carlo techniques. Because of this work, it is now possible to perform computer simulation of protein-quantum dot complexes that were previously considered to be beyond the scope of computational investigations. Now that this methodology has been created, it can be applied to bigger and more complex quantum dot systems.
Their paper, "Optical Signature of Formation of Protein Corona in the Firefly Luciferase-CdSe Quantum Dot Complex" is featured on the cover of the January issue of the Journal of Chemical Theory and Computation.
Matt Wheeler | EurekAlert!
Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
09.12.2016 | Cold Spring Harbor Laboratory
Plant-based substance boosts eyelash growth
09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
09.12.2016 | Life Sciences
09.12.2016 | Ecology, The Environment and Conservation
09.12.2016 | Health and Medicine