Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Nanotechnology with proteins

15.09.2015

Göttingen scientists test new method of constructing two-dimensional structures

For over two decades, scientists have been using DNA to design nanomaterials. Researchers from the University of Göttingen and the Medical School Hanover, both in Germany, have now discovered a new method to use proteins to construct two-dimensional webbings. The results were published in the scientific journal Nature Nanotechnology.


Electron micrograph of a rough aluminium surface coated with a regular clathrin webbing (size is approximately 1.5 x 1.5 micrometers).

Foto: Universität Göttingen

The use of proteins in nanotechnology is a largely unexplored area. "However, due to their complex structure, proteins offer many possibilities to develop novel materials with unique properties," explains Dr. Iwan A.T. Schaap from Göttingen University’ Third Institute of Physics.

The protein clathrin is normally involved in the formation of transport vesicles inside cells. The scientists show in their study that clathrin can also be used to form two-dimensional webbings on almost any type of surface. "This could revolutionize the design of biological sensors and biosynthetic reactors," says Dr. Schaap.

After the researchers composed the clathrin-building blocks into a regular hexagonal lattice with a periodicity of only 30 nanometers, they developed a stabilization scheme. "It is essential that the protein structures are robust so that the nanotechnological devices will have a long lifetime and shelf-life," explains Dr. Schaap.

Finally, the researchers showed how the clathrin webbings can be converted into functional devices by the binding of small metallic particles and active biomolecules.

The researchers will continue their work on these novel protein structures with the aim of developing more efficient nanotechnological devices that can be used for sensing applications and the synthesis of biomolecules.

Original publication: Philip N. Dannhauser et al. Durable protein lattices of clathrin that can be functionalized with nanoparticles and active biomolecules. Nature Nanotechnology 2015. Doi: 10.1038/nnano.2015.206.

Contact:
Dr. Iwan A.T. Schaap
Georg-August-Universität Göttingen
Faculty of Physics – III. Physical Institute
Friedrich-Hund-Platz 1, 37077 Göttingen, Germany
Phone +49 551 39-22816
Email: ischaap@gwdg.de

Weitere Informationen:

http://www.iwanschaap.com

Thomas Richter | idw - Informationsdienst Wissenschaft

More articles from Life Sciences:

nachricht 'Lipid asymmetry' plays key role in activating immune cells
20.02.2018 | Biophysical Society

nachricht New printing technique uses cells and molecules to recreate biological structures
20.02.2018 | Queen Mary University of London

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

'Lipid asymmetry' plays key role in activating immune cells

20.02.2018 | Life Sciences

MRI technique differentiates benign breast lesions from malignancies

20.02.2018 | Medical Engineering

Major discovery in controlling quantum states of single atoms

20.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>