With their specialized diet of almost exclusively Eucalyptus leaves, do koalas require specialist microbes to help them digest their food? Scientists from the Leibniz Institute for Zoo and Wildlife Research (IZW) investigated the composition of bacterial communities in different digestion-associated organs but found no unusual or special microbial communities when they compared these with those of other mammals.
The study also demonstrates that non-invasive samples such as faecal samples commonly used to assess the composition of microbial communities may not provide an accurate account of the host gut microbiome. The study has just been published in the scientific journal “Scientific Reports”.
The koala (Phascolarctos cinereus) is an arboreal marsupial that has a unique diet consisting almost exclusively of Eucalyptus leaves. Eucalyptus foliage has been described as an “unpromising” dietary source for being low in nutrients but rich in compounds which are toxic to most animals.
Bacteria are thought to play an important role in the digestion of Eucalyptus leaves. However, whether such an exclusive diet influences the composition of koala bacterial communities, or microbiomes, is unknown.
An international team of scientists from the Department of Wildlife Diseases of the Leibniz Institute for Zoo and Wildlife Research (IZW) in Berlin, Germany, University of the Sunshine Coast (Australia), University of Illinois at Urbana-Champaign (USA) and Vienna Zoological Garden characterised the koala microbiomes using next generation sequencing.
The scientists found that koala oral and gut microbiomes were similar in composition to the microbiomes from the same body regions of other mammalian species. Therefore the unique diet of koalas does not seem to influence koala microbial communities inhabiting digestion-associated organs. Furthermore, rectal swabs and faeces were compared, for the first time using high-throughput sequencing, in order to understand whether these two sample types are equivalent in describing koala gut microbiome.
Rectal swabs contained all of the diversity present in faecal samples, along with additional taxa, suggesting that faecal bacterial communities may only represent a subsample of the complex bacterial communities inhabiting the gut. Moreover, the faecal microbiomes of the captive koalas from this study were compared with existing data on wild koalas to understand whether captivity results in major alterations of koala gut microbiome.
The results showed that the profile of captive and wild koalas were similar, suggesting that captivity may not compromise koala microbial health. Because koalas frequently suffer from ocular diseases caused by Chlamydia infection, the microbiome of the koala eye was also examined. This microbial community was very diverse, similar to other mammalian ocular microbiomes but with an unusually high representation of bacteria from a family not observed in other mammals.
Further research will be needed to determine whether this influences the susceptibility of koalas to infections by Chlamydia. This is the first study describing the composition of the eye microbiome of a non-human mammal by high-throughput sequencing and it establishes the healthy baseline for this body part to which microbiomes of diseased states can be compared.
Alfano N, Courtiol A, Vielgrader H, Timms P, Roca AL, Greenwood AD (2015): Variation in koala microbiomes within and between individuals: effect of body region and captivity status. SCI REP. Doi: 10.1038/srep10189.
Leibniz Institute for Zoo and Wildlife Research (IZW)
Tel.: +49 30 5168-455
Tel.: +49 30 5168-125
Saskia Donath | Forschungsverbund Berlin e.V.
New risk factors for anxiety disorders
24.02.2017 | Julius-Maximilians-Universität Würzburg
Stingless bees have their nests protected by soldiers
24.02.2017 | Johannes Gutenberg-Universität Mainz
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
24.02.2017 | Life Sciences
24.02.2017 | Life Sciences
24.02.2017 | Trade Fair News