In 2014, when University of Wisconsin-Madison engineers announced in the journal Nature Communications that they had developed transparent sensors for use in imaging the brain, researchers around the world took notice.
Then the requests came flooding in. "So many research groups started asking us for these devices that we couldn't keep up," says Zhenqiang (Jack) Ma, the Lynn H. Matthias Professor and Vilas Distinguished Achievement Professor in electrical and computer engineering at UW-Madison.
Ma's group is a world leader in developing revolutionary flexible electronic devices. The see-through, implantable micro-electrode arrays were light years beyond anything ever created.
Although he and collaborator Justin Williams, the Vilas Distinguished Achievement Professor in biomedical engineering and neurological surgery at UW-Madison, patented the technology through the Wisconsin Alumni Research Foundation, they saw its potential for advancements in research. "That little step has already resulted in an explosion of research in this field," says Williams. "We didn't want to keep this technology in our lab. We wanted to share it and expand the boundaries of its applications."
As a result, in a paper published Thursday (Oct. 13, 2016) in the journal Nature Protocols, the researchers have described in great detail how to fabricate and use transparent graphene neural electrode arrays in applications in electrophysiology, fluorescent microscopy, optical coherence tomography, and optogenetics. "We described how to do these things so we can start working on the next generation," says Ma.
Now, not only are the UW-Madison researchers looking at ways to improve and build upon the technology, they also are seeking to expand its applications from neuroscience into areas such as research of stroke, epilepsy, Parkinson's disease, cardiac conditions, and many others. And they hope other researchers do the same.
"This paper is a gateway for other groups to explore the huge potential from here," says Ma. "Our technology demonstrates one of the key in vivo applications of graphene. We expect more revolutionary research will follow in this interdisciplinary field."
Funding for the initial research came from the Reliable Neural-Interface Technology program at the U.S. Defense Advanced Research Projects Agency. Other authors on the Nature Protocols paper include Dong-Wook Park, Sarah Brodnick, Jared Ness, Lisa Krugner-Higby, Solomon Mikael, Joseph Novello, Hyungsoo Kim, Dong-Hyun Baek, Jihye Bong, Kyle Swanson and Wendell Lake of UW-Madison; Farid Atry, Seth Frye and Ramin Pashaie of the University of Wisconsin-Milwaukee; Amelia Sandberg of Medtronic PLC Neuromodulation; Thomas Richner of the University of Washington; and Sanitta Thongpang of Mahidol University in Bangkok, Thailand.
Renee Meiller, email@example.com, (608) 262-2481
DOWNLOAD PHOTO: https:/
Zhenqiang (Jack) Ma | EurekAlert!
Did you know that the wrapping of Easter eggs benefits from specialty light sources?
13.04.2017 | Heraeus Noblelight GmbH
To e-, or not to e-, the question for the exotic 'Si-III' phase of silicon
05.04.2017 | Carnegie Institution for Science
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences