Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


IMP-Researcher Johannes Zuber wins German Cancer Prize


Johannes Zuber, group leader at the Research Institute of Molecular Pathology (IMP) in Vienna, receives the German Cancer Prize 2016 in the category of experimental cancer research. This was announced today at the opening ceremony of the German Cancer Congress in Berlin.

The German Cancer Prize (Deutscher Krebspreis) is one of the most prestigious scientific awards in the German speaking world and annually honours researchers for groundbreaking discoveries in the field of oncology.

IMP Group Leader Johannes Zuber

Copyright: IMP/Fischer

This year's award acknowledges the achievements of Johannes Zuber, whose contributions have shaped the field of functional cancer genetics. Together with his team at the IMP, the physician scientist uses innovative genetic approaches to identify and study genes that are required for the survival of cancer cells and serve as candidate targets for the development of new cancer therapies.

Through developing and applying optimised RNAi-screening methods, Zuber discovered the gene BRD4 as a genetic vulnerability and candidate target for the treatment of acute myeloid leukemia (AML), an aggressive form of blood cancer.

After BRD4 inhibitors have already shown promising effects in AML and other malignancies, his research team could recently identify molecular mechanisms that render leukemia cells resistant to these agents. These insights are of great importance for the future development of BRD4 inhibitors in the clinic.

“This award is a great honour and encouragement to further expand our research in the field of functional cancer genetics”, says Johannes Zuber. He points out that new genetic tools offer fascinating opportunities for finding and probing therapeutic targets such as BRD4: “We are currently witnessing a true revolution in functional genetics, which will enable us to search for better cancer therapies in entirely new ways.”

Johannes Zuber, born 1974 in Dresden, completed his medical studies and a doctoral thesis in molecular cancer research at Berlin’s Charité Medical School in 2003. During his residency in hematology/oncology at the Charité University Hospital, leukemia became the focus of his scientific interest. In 2005, Zuber moved to the US to join Scott Lowe's lab at the renowned Cold Spring Harbor Laboratory, where he developed innovative genetic models to study targeted therapies in leukemia. In 2011, he founded his own lab at the IMP in Vienna.

The German Cancer Prize is endowed with 22,500 Euros and awarded annually by the “Deutsche Krebsgesellschaft” (German Cancer Society) and the “Deutsche Krebsstiftung” (German Cancer Foundation) for groundbreaking work in three categories: experimental research, translational research and clinical research in oncology.

The criteria are exceptional scientific quality and originality of research in the field of oncology. Former awardees include renowned scientists such as Nobel laureate Harald zur Hausen, Peter Krammer, Axel Ullrich or Walter Birchmeier. Johannes Zuber is the first recipient who is affiliated with an institution in Austria.

About the IMP
The Research Institute of Molecular Pathology (IMP) in Vienna is a basic biomedical research institute largely sponsored by Boehringer Ingelheim. With over 200 scientists from 37 nations, the IMP is committed to scientific discovery of fundamental molecular and cellular mechanisms underlying complex biological phenomena. Research areas include cell and molecular biology, neurobiology, disease mechanisms and computational biology.

Media Contact at the IMP
Dr. Heidemarie Hurtl
IMP Communications
Research Institute of Molecular Pathology
Dr. Bohr-Gasse 7
A 1030 Vienna
+43 (0)1 79730 3625

Weitere Informationen:

Dr. Heidemarie Hurtl | idw - Informationsdienst Wissenschaft

More articles from Awards Funding:

nachricht Innovation Award of the United Nations Environment Programme for PhD Student from ZMT
22.03.2018 | Leibniz-Zentrum für Marine Tropenforschung (ZMT)

nachricht ERC Project set to boost application of adhesive structures
19.03.2018 | INM - Leibniz-Institut für Neue Materialien gGmbH

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Researchers Discover New Anti-Cancer Protein

An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.

The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...

Im Focus: Researchers at Fraunhofer monitor re-entry of Chinese space station Tiangong-1

In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.

Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...

Im Focus: Alliance „OLED Licht Forum“ – Key partner for OLED lighting solutions

Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.

They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...

Im Focus: Mars' oceans formed early, possibly aided by massive volcanic eruptions

Oceans formed before Tharsis and evolved together, shaping climate history of Mars

A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...

Im Focus: Tiny implants for cells are functional in vivo

For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.

In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...

All Focus news of the innovation-report >>>



Industry & Economy
Event News

Virtual reality conference comes to Reutlingen

19.03.2018 | Event News

Ultrafast Wireless and Chip Design at the DATE Conference in Dresden

16.03.2018 | Event News

International Tinnitus Conference of the Tinnitus Research Initiative in Regensburg

13.03.2018 | Event News

Latest News

Modular safety concept increases flexibility in plant conversion

22.03.2018 | Trade Fair News

New interactive map shows climate change everywhere in world

22.03.2018 | Earth Sciences

New technologies and computing power to help strengthen population data

22.03.2018 | Earth Sciences

Science & Research
Overview of more VideoLinks >>>