Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

ERC Grant for new Therapy against Burn Scars

26.01.2016

Major accolade for Professor Ursula Mirastschijski from the Center for Biomolecular Interactions in Faculty Biology/Chemistry, who has received a grant from the European Research Council (ERC) to develop a novel therapy against burn scars. People who have suffered severe burns are very often scarred for life. In future it is expected that the new therapy will prevent such scar formation. Last year the ERC supported her project with an ERC Starting Grant in an amount of 1.3 million euros. As of March 1, 2016, the ERC support will be extended for a further year via a Proof of Concept Grant worth 150,000 euros.

For their novel therapy to prevent scar formation, Ursula Mirastschijski and her team use a substance produced in our lungs called lung surfactant. This substance coats the lung’s surface, preventing it from collapsing when we breathe out. Humans automatically produce this substance from birth. Premature babies have to have the substance injected into their lungs to help them breathe.


Professor Ursula Mirastschijski from the Faculty of Biology/Chemistry has been awarded her second ERC grant.

Harald Rehling / Universität Bremen

Professor Mirastschijski and her team discovered that the substance inhibits inflammation and has wound-healing properties. So they asked themselves, “Why shouldn’t it also work on skin burns?” The first year of the research project SUMOWO (A Surface modulation of Wounds: heal by inhalants! Novel drug-based treatment for excessive scars and chronic wounds) proved very promising.

The University of Bremen researcher and plastic surgeon will use the bolt-on financing to carry out clinical tests at the hospital Klinikum Bremen-Mitte. She is now looking for suitable candidates for skin tests. “The tests are painless and perfectly harmless”, she stresses. If you are interested in becoming a test person, please send a mail to: ursula.mirastschijski@klinikum-bremen-mitte.de.

Fourth ERC Grant for researchers in Faculty Biology/Chemistry

ERC grants are among Europe’s most prestigious and coveted awards for researchers. The University of Bremen is quite outstanding in this regard, for there are now three female professors in the Faculty of Biology/Chemstry, Ursula Mirastschijski, Katrin Mädler and Rita Groß-Hardt, who between them have received four ERC grants. “This underscores the high level of molecular-biological research and sustainable gender mainstreaming practiced at the University of Bremen”, says Mirastschijski.

“I count myself fortunate to be able to do my research here.” She says she finds optimal conditions and support for her work here. Flat hierarchies and short administrative pathways facilitate smooth-functioning interdisciplinary cooperation and provide scope for innovative ideas. “All this is quite unique”, she says.

VolkswagenStiftung is supporting a further innovative project on wound healing

In addition to the above, Professor Ursula Mirastschijski is also receiving support for separate project on treating wounds and repairing skin tissue: She has been awarded 100,000 euros within the context of the Volkswagen Foundation’s funding initiative titled “Experiment”.

In this cooperation project, Ursula Mirastschijski and her project partners are attempting to manipulate skin cells so that they produce oxygen, which in turn then promotes the healing of chronic tissue damage. “Millions of years ago, plant life developed the ability to photosynthesize, which entails producing oxygen from sunlight”, Mirastschijski explains. “So what could be more natural than to utilize this way of producing oxygen to help heal wounds?”

On this project, she is working together with Professor Michael Vellekoop from the Institute for Microsensors, -Actuators and –Systems (IMSAS) embedded in the Faculty Physics/Electrical Engineering and Professor Anya Waite from the Alfred Wegener Institute, Helmholtz Center for Polar and Marine Research (AWI) in Bremerhaven. Professor Vellekoop is developing the microsensors needed to measure the oxygen, and Professor Waite is contributing her expertise in the field of oceanology.

Cooperation between the University and Klinikum Bremen-Mitte

Ursula Mirastschijski moved to the University of Bremen from the Medical University of Hanover in 2013, bringing her research group called “Wound Repair Unit” with her. Since 2012, she also works as a plastic surgeon at Klinikum Bremen-Mitte, and she is a senior physician at the Clinic for Plastic, Reconstructive, and Aesthetical Surgery. “My applied research wouldn’t be possible without this close cooperation between University and clinic”, says Ursula Mirastschijski.

About Ursula Mirastschijski

Professor Ursula Mirastschijski studies medicine at the University of Ulm, where she was also awarded her doctorate. Following periods of clinical research in Sweden and Denmark and completion of her Ph.D. project she trained as a consultant for plastic and aesthetical surgery at the Otto-von-Guericke University of Magdeburg and at the Medical University of Hanover, where she submitted her post-doctoral dissertation in 2010 and was appointed to a professorship in 2015. She continued teaching as a professor at the Medical University of Hanover and Klinikum Bremen-Mitte. Among other things, she is member of the German Association of Plastic, Reconstructive and Aesthetical Surgeons and member of the board of the European Tissue Repair Society.

If you would like to have more information on this topic, please contact:

University of Bremen
Faculty Biology/Chemistry
Center for Biomolecular Interactions
Prof. Dr. med. Dr. phil. Ursula Mirastschijski
Phone: 0421 218-63224
e-mail: mirastsc@uni-bremen.de
  www.cbib.uni-bremen.de/en/cbib

Meike Mossig | idw - Informationsdienst Wissenschaft

More articles from Awards Funding:

nachricht Tracking down the origins of gold
08.11.2017 | Heidelberger Institut für Theoretische Studien gGmbH

nachricht Lasagni awarded with Materials Science and Technology Prize 2017
09.10.2017 | Fraunhofer-Institut für Werkstoff- und Strahltechnik IWS

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Previous evidence of water on mars now identified as grainflows

21.11.2017 | Physics and Astronomy

NASA's James Webb Space Telescope completes final cryogenic testing

21.11.2017 | Physics and Astronomy

New catalyst controls activation of a carbon-hydrogen bond

21.11.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>