NOVEL SELECTIVE CYP11B1 INHIBITORS
The corticosteroid cortisol is synthesized in the adrenal cortex by a complex reaction cascade. The final step of the cortisol synthesis is catalyzed by CYP11B1. Due to the involvement of cortisol in many physiological processes a pathological overproduction might result in different diseases.
Scientist of Saarland University have now managed to develop the first CYP11B1 inhibitors showing a selective effect, i.e. they are effective on CYP11B1 nearly exclusively. Moreover the new inhibitors act with a very high degree of efficiency.
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Universität des Saarlandes Wissens- und Technologietransfer GmbH PatentVerwertungsAgentur der saarländischen Hochschulen
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Dr. Annekathrin Seifert (Dipl.-Chem.), Dipl.-Kfm. Axel Koch (MBA), Dr. Hauke Studier (Dipl.-Phys.)
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