NOVEL SELECTIVE CYP11B1 INHIBITORS

The corticosteroid cortisol is synthesized in the adrenal cortex by a complex reaction cascade. The final step of the cortisol synthesis is catalyzed by CYP11B1. Due to the involvement of cortisol in many physiological processes a pathological overproduction might result in different diseases.

Scientist of Saarland University have now managed to develop the first CYP11B1 inhibitors showing a selective effect, i.e. they are effective on CYP11B1 nearly exclusively. Moreover the new inhibitors act with a very high degree of efficiency.

Further Information: PDF

Universität des Saarlandes Wissens- und Technologietransfer GmbH PatentVerwertungsAgentur der saarländischen Hochschulen
Phone: +49 (0)681/302-6340

Contact
Dr. Annekathrin Seifert (Dipl.-Chem.), Dipl.-Kfm. Axel Koch (MBA), Dr. Hauke Studier (Dipl.-Phys.)

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info@technologieallianz.de TechnologieAllianz e.V.

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